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一例血液病继发侵袭性肺部毛霉菌病(微小毛霉)。

A Case of Invasive Pulmonary Mycosis (Rhizopus microspores) secondary to Hematological Disease.

出版信息

Clin Lab. 2024 Aug 1;70(8). doi: 10.7754/Clin.Lab.2024.240331.

Abstract

BACKGROUND

Pulmonary mucormycosis is most common in patients with hematologic malignancies and transplant recipients. This article describes a case of mucormycosis in the lungs secondary to a hematologic disorder with suspected lung cancer.

METHODS

Rhizopus (Rhizopus microspores) was detected by blood NGS and bronchoalveolar lavage fluid NGS, and pulmonary mucormycosis was confirmed.

RESULTS

Secondary to hematologic disease, pulmonary pneumonia, mycosis, and symptoms improved after comprehensive treatment.

CONCLUSIONS

Clinical data and radiologic knowledge are combined to diagnose invasive pulmonary mycoses; early empirical medicine is very important.

摘要

背景

肺毛霉病最常见于血液恶性肿瘤和移植受者患者。本文描述了一例血液系统疾病继发肺毛霉病,疑似肺癌。

方法

血液 NGS 和支气管肺泡灌洗液 NGS 检测到根霉(Rhizopus microspores),确诊为肺毛霉病。

结果

继发于血液系统疾病,肺部肺炎、真菌感染,综合治疗后症状改善。

结论

结合临床数据和影像学知识诊断侵袭性肺部真菌感染;早期经验性用药非常重要。

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