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泌尿外科恶性肿瘤腹腔镜根治性手术中术前灌注指数与术中低体温的相关性

The Correlation Between Preoperative Perfusion Index and Intraoperative Hypothermia During Laparoscopic Radical Surgery for Urological Malignancies.

作者信息

Zhang Yingying, Li Yuxiao, Chen Fengxia

机构信息

Operating Room, The First Affiliated Hospital of Harbin Medical University, Harbin Medical University, Harbin, China.

Nursing School, Sanquan College of Xinxiang Medical University, Xinxiang, China.

出版信息

Ther Hypothermia Temp Manag. 2025 Jun;15(2):82-88. doi: 10.1089/ther.2024.0035. Epub 2024 Aug 28.

Abstract

This study aimed to explore the relationship between preoperative baseline perfusion index (PI) and intraoperative hypothermia during general anesthesia. PI reflects the peripheral perfusion status, which may be associated with the decrease of core temperature during general anesthesia, as the redistribution of temperature from the core compartment to the peripheral compartment depends on the peripheral perfusion status. A total of 68 patients underwent radical surgery for urological malignancies in this study. The baseline PI value was measured upon entering the operating room. Core temperature was continuously monitored using a nasal pharyngeal probe from anesthesia induction to the end of surgery, with temperature data recorded every 15 minutes. Univariate and multivariate logistic regression analyses were used to identify risk factors for intraoperative hypothermia. Intraoperative hypothermia occurred in 26 patients, whose baseline PI (2.70 ± 0.73) was significantly lower than that of the normothermic group (3.65 ± 1.05), with <0.05. The baseline PI was independently associated with intraoperative hypothermia (PI: [OR] 0.375, 95% confidence interval [CI]: 1.584-6.876, = 0.001). This study suggests that low baseline PI is an independent factor associated with intraoperative hypothermia. In future studies, PI value could be considered as a predictor for the treatment of intraoperative hypothermia.

摘要

本研究旨在探讨全身麻醉期间术前基线灌注指数(PI)与术中体温过低之间的关系。PI反映外周灌注状态,这可能与全身麻醉期间核心温度的降低有关,因为温度从核心腔室向外周腔室的重新分布取决于外周灌注状态。本研究共纳入68例接受泌尿外科恶性肿瘤根治性手术的患者。进入手术室时测量基线PI值。从麻醉诱导至手术结束,使用鼻咽探头持续监测核心温度,每15分钟记录一次温度数据。采用单因素和多因素逻辑回归分析来确定术中体温过低的危险因素。26例患者发生术中体温过低,其基线PI(2.70±0.73)显著低于体温正常组(3.65±1.05),P<0.05。基线PI与术中体温过低独立相关(PI:[比值比]0.375,95%置信区间[CI]:1.584 - 6.876,P = 0.001)。本研究表明,低基线PI是与术中体温过低相关的独立因素。在未来的研究中,PI值可被视为治疗术中体温过低的一个预测指标。

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