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Chem Pharm Bull (Tokyo). 2023;71(2):134-139. doi: 10.1248/cpb.c22-00651.
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Efficacy and safety of adjunctive therapy to lamotrigine, lithium, or valproate monotherapy in bipolar depression: a systematic review and meta-analysis of randomized controlled trials.拉莫三嗪、锂盐或丙戊酸盐单药治疗双相抑郁的辅助治疗的疗效与安全性：一项随机对照试验的系统评价和荟萃分析
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The Comorbidity of Schizophrenia Spectrum and Mood Disorders in Autism Spectrum Disorder.自闭症谱系障碍中精神分裂症谱系和情绪障碍的共病现象。
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《日本心境障碍学会双相障碍治疗指南》

Practice Guidelines for Bipolar Disorder by the JSMD (Japanese Society of Mood Disorders).

机构信息

Department of Psychiatry & Behavioral Science, Juntendo University Graduate School of Medicine, Tokyo, Japan.

Center for Postgraduate Clinical Training and Career Development, Nagoya University Hospital, Nagoya, Japan.

出版信息

Psychiatry Clin Neurosci. 2024 Nov;78(11):633-645. doi: 10.1111/pcn.13724. Epub 2024 Aug 28.

DOI:10.1111/pcn.13724
PMID:39194164
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11804931/
Abstract

The Japanese Society of Mood Disorders (JSMD) published treatment guidelines of bipolar disorder in 2011. The present guidelines incorporating new findings were developed to comply to the guidelines of the National Academy of Medicine (NAM) by utilizing systematic reviews and meta-analysis and taking patient and family opinions as well as insights from multiple professional fields into account. They support combination therapy using mood stabilizers and second-generation antipsychotics in many aspects. They also have limitations, including the grouping of mood stabilizers and second-generation antipsychotics when meta-analysis was performed despite their distinct properties, due to the scarcity of drug-specific evidence. Despite the limitations, these guidelines provide clinical decision support for psychiatrists in Japan.

摘要

日本心境障碍学会（JSMD）于 2011 年发布了双相障碍治疗指南。本指南结合了新的研究结果，旨在遵循国家医学院（NAM）的指南，利用系统评价和荟萃分析，并考虑患者和家属的意见以及来自多个专业领域的见解。它们在许多方面支持使用心境稳定剂和第二代抗精神病药物的联合治疗。它们也存在局限性，包括在进行荟萃分析时，尽管心境稳定剂和第二代抗精神病药物具有不同的特性，但由于缺乏特定药物的证据，因此将它们分组。尽管存在这些局限性，但这些指南为日本的精神科医生提供了临床决策支持。