Managing vitreoretinal complications in uveal melanoma: Surgical treatment and practical considerations.
作者信息
Anguita Rodrigo, Chou Hung-Da, Raval Vishal R, Bajpai Vidhi, Ferro Desideri Lorenzo, Bernardi Enrico, Hussain Rumana N, Kim Min, Fung Adrian T, Williams Basil K, Di Nicola Maura, Sagoo Mandeep S, da Cruz Lyndon, Damato Bertil, Kiilgaard Jens Folke
机构信息
Department of Ophthalmology, Inselspital, University Hospital of Bern, Bern, Switzerland.
NIHR Biomedical Research Centre for Ophthalmology, Moorfields Eye Hospital and UCL Institute of Ophthalmology, London, UK.
出版信息
Semin Ophthalmol. 2025 Nov;40(8):709-718. doi: 10.1080/08820538.2024.2381774. Epub 2024 Aug 28.
BACKGROUND
In the past few decades, the primary management for uveal melanoma has evolved from enucleation to eye-preserving treatments. However, despite achieving a high rate of local tumour control, complications following eye-preserving treatments still occur and are partly responsible for functional loss and secondary enucleation.
METHODS
A literature review by a broad international panel.
RESULTS
We summarised the current literature on utilizing vitreoretinal (VR) surgery for managing the complications of uveal melanoma. We also provided insights from the authors' personal experience and practical recommendations for clinical care.
CONCLUSIONS
With the advancement of VR instruments and surgical techniques and the combination of VR and ocular oncology knowledge ("Onco-VR"), it is now possible to manage or even prevent complications such as vitreous haemorrhage, retinal detachment, and toxic tumour syndrome.
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