Sá Manuel, Faria Carlos, Pozza Daniel Humberto
Experimental Biology Unit, Department of Biomedicine, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal.
Department of Surgery and Physiology, Faculty of Medicine of Porto, University of Porto, 4200-319 Porto, Portugal.
Dent J (Basel). 2024 Jul 31;12(8):244. doi: 10.3390/dj12080244.
Temporomandibular disorders (TMDs) frequently cause orofacial pain and dysfunction, with treatment options spanning from conservative therapies to invasive surgical procedures. The aim of this systematic review was to analyze and compare the efficacy and safety profiles of conservative, minimally invasive interventions and surgical procedures in patients diagnosed with TMDs and disc displacement.
Following PRISMA recommendations, PubMed, Scopus, and Web of Science databases were searched for randomized clinical trials (RCT). Data were synthesized in a table and evaluated through the Cochrane risk of bias 2 (RoB 2) tool.
Thirty-eight RCTs, most with moderate RoB, were selected. Conservative approaches, including physical therapy and occlusal devices, led to an improvement in symptoms and function. Pharmacological treatments demonstrated effectiveness in reducing pain and improving function; however, they can have undesirable side effects. Minimally invasive and invasive treatments also demonstrated efficacy, although most trials did not show their superiority to conservative treatments.
The primary approach to TMDs should be a conservative, multimodal treatment plan tailored to patient complaints and characteristics. Treatment goals should focus on symptom control and functional recovery. Surgical treatment should be reserved for cases with a precise diagnosis and a clear etiology.
颞下颌关节紊乱病(TMDs)常导致口面部疼痛和功能障碍,治疗方案涵盖从保守治疗到侵入性外科手术。本系统评价的目的是分析和比较保守治疗、微创干预和手术治疗对诊断为TMDs和关节盘移位患者的疗效和安全性。
按照PRISMA推荐,检索PubMed、Scopus和Web of Science数据库中的随机临床试验(RCT)。数据汇总于表格中,并通过Cochrane偏倚风险2(RoB 2)工具进行评估。
共纳入38项RCT,多数偏倚风险为中度。保守治疗方法,包括物理治疗和咬合装置,可改善症状和功能。药物治疗在减轻疼痛和改善功能方面有效;然而,可能会有不良副作用。微创和侵入性治疗也显示出疗效,尽管大多数试验未显示其优于保守治疗。
TMDs的主要治疗方法应是根据患者主诉和特征制定的保守、多模式治疗方案。治疗目标应侧重于症状控制和功能恢复。手术治疗应仅用于诊断明确且病因清晰的病例。