脑海绵状血管畸形蛋白在血管生理学中的复兴。
A renaissance of cerebral cavernous malformation proteins in vascular physiology.
作者信息
Abdelilah-Seyfried Salim, Jo Hanjoong
机构信息
Institute of Biochemistry and Biology, Potsdam University, Potsdam, Germany.
Wallace H. Coulter Department of Biomedical Engineering, Emory University & Georgia Tech, Atlanta, GA, USA.
出版信息
Nat Cardiovasc Res. 2024 Jul;3(7):771-773. doi: 10.1038/s44161-024-00504-1.
Abstract
The discovery of the genes causing cerebral cavernous malformation (CCM) initially heralded a fruitful search for etiopathogenic molecular pathways in this rare cerebrovascular disease. Recent studies have identified the relevance of CCM proteins for much more common vascular biology and pathologies.
摘要
导致脑海绵状血管畸形（CCM）的基因的发现，最初预示着在这种罕见的脑血管疾病中对病因分子途径的探索将卓有成效。最近的研究已经确定CCM蛋白与更为常见的血管生物学和病理学的相关性。
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