Hagendorff Andreas, Stöbe Stephan, Helfen Andreas, Knebel Fabian, Altiok Ertunc, Beckmann Stephan, Bekfani Tarek, Binder Thomas, Ewers Aydan, Hamadanchi Ali, Freyhaus Henrik Ten, Groscheck Thomas, Haghi Dariush, Knierim Jan, Kruck Sebastian, Lenk Karsten, Merke Nicolas, Pfeiffer Dietrich, Dorta Elena Romero, Ruf Tobias, Sinning Christoph, Wunderlich Nina C, Brandt Roland, Ewen Sebastian
Department of Cardiology, University Hospital Leipzig AöR, Leipzig, Germany.
Department of Kardiologie, Katholische St. Paulus Gesellschaft, St.-Marien-Hospital Lünen, Lünen, Germany.
Clin Res Cardiol. 2025 Jan;114(1):25-40. doi: 10.1007/s00392-024-02492-5. Epub 2024 Aug 28.
The left atrial appendage is a blind ending cardiac structure prone to blood stasis due to its morphology. This structure is a preferred region of thrombogenesis in relation to reduced myocardial contractility of the atrial wall. Blood stasis occurs primarily in low flow conditions. One of the tasks of echocardiography is the analysis of morphology and function of the left atrial appendage. The detection of thrombi by echocardiography is difficult and must be carried out thoroughly and carefully to avoid potential complications-especially in the context of rhythm control. The assessment of thromboembolic risk, especially in patients with unknown and presumed atrial fibrillation is a second challenge by characterizing atrial function and flow conditions in the left atrial appendage. Thus, this proposal focuses on the obvious problems of echocardiography when assessing left atrial appendage and the role of this method in planning a potential interventional closure of left atrial appendage.
左心耳是一个盲端心脏结构，因其形态易发生血液淤滞。相对于心房壁心肌收缩力降低，该结构是血栓形成的首选部位。血液淤滞主要发生在低血流状态下。超声心动图的任务之一是分析左心耳的形态和功能。通过超声心动图检测血栓很困难，必须全面、仔细地进行，以避免潜在并发症——尤其是在节律控制的情况下。评估血栓栓塞风险，特别是在不明和疑似房颤患者中，是通过描述左心耳的心房功能和血流状况面临的第二个挑战。因此，本提议聚焦于评估左心耳时超声心动图存在的明显问题，以及该方法在规划左心耳潜在介入封堵中的作用。
