Ware Megan E, Goodenough Chelsea G, Wogksch Matthew D, Krull Kevin R, Brinkman Tara M, Hebert James R, Willard Victoria, Webster Rachel, Ehrhardt Matthew, Mirzaei Sedigheh, Armstrong Gregory T, Hudson Melissa M, Ness Kirsten K
Department of Epidemiology and Cancer Control, St. Jude Children's Research Hospital, Memphis, TN, USA.
Department of Kinesiology, Health Promotion, and Recreation, University of North Texas, Denton, TX, USA.
J Cancer Surviv. 2024 Aug 28. doi: 10.1007/s11764-024-01667-3.
Perceived cancer impact (PCI) is the degree to which one feels cancer has impacted one's life. It is unknown if PCI is associated with health behaviors. The aim of this study is to determine associations between PCI and health behaviors in childhood cancer survivors.
Participants were ≥ 5-year survivors enrolled in the St. Jude Lifetime (SJLIFE) cohort. The Brief Cancer Impact (BCIA) assessed PCI across four domains (caregiving/finances, diet/exercise, social/emotional functioning, religiosity). Responses were categorized as negative, neutral, or positive impact. Smoking, risky drinking, illicit drug use, and diet quality data were obtained via self-report. Physical activity (PA) was assessed via self-report and actigraphy. Cross-sectional and longitudinal associations between PCI and health behaviors were evaluated via multivariable logistic regression.
A total of 3623 participants (mean age 30.4 ± 8.3 years, 49.6% female, 81.5% NH White) were included in baseline cross-sectional analysis; 1709 had a second visit 5.0 ± 1.4 years later and were included in longitudinal analysis. At baseline, the percentage of participants who endorsed cancer as having a negative impact on caregiving/finances was 37.5%, diet/exercise 30.5%, social/emotional functioning 40.6%, and religiosity 8.7%. Negative and neutral PCI across all four domains were cross-sectionally associated with all behaviors except illicit drug use. Negative and neutral PCI at the first time point across all four domains were associated with smoking, diet quality, and PA (ORs ranging from 1.35 to 2.41) in longitudinal analyses.
Endorsing negative or neutral PCI is associated with adverse health behaviors.
Promoting optimal health behavior should include addressing PCI.
感知到的癌症影响（PCI）是指一个人感觉癌症对其生活产生影响的程度。PCI是否与健康行为相关尚不清楚。本研究的目的是确定儿童癌症幸存者中PCI与健康行为之间的关联。
参与者为≥5岁的圣裘德终身（SJLIFE）队列研究的幸存者。简短癌症影响量表（BCIA）从四个领域评估PCI（护理/财务、饮食/运动、社会/情感功能、宗教信仰）。回答被分类为负面影响、中性影响或正面影响。吸烟、危险饮酒、非法药物使用和饮食质量数据通过自我报告获得。身体活动（PA）通过自我报告和活动记录仪进行评估。通过多变量逻辑回归评估PCI与健康行为之间的横断面和纵向关联。
共有3623名参与者（平均年龄30.4±8.3岁，49.6%为女性，81.5%为非西班牙裔白人）纳入基线横断面分析；1709人在5.0±1.4年后进行了第二次随访并纳入纵向分析。在基线时，认可癌症对护理/财务有负面影响的参与者百分比为37.5%，对饮食/运动为30.5%，对社会/情感功能为40.6%，对宗教信仰为8.7%。除非法药物使用外，所有四个领域的负面和中性PCI与所有行为均存在横断面关联。在纵向分析中，所有四个领域在第一个时间点的负面和中性PCI与吸烟、饮食质量和PA相关（比值比范围为1.35至2.41）。
认可负面或中性PCI与不良健康行为相关。
促进最佳健康行为应包括关注PCI。
