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法洛四联症修复术后的室性心律失常。附59例报告

[Ventricular arrhythmia following repair of Fallot's tetralogy. Apropos of 59 cases].

作者信息

Matina D, Mouly A, Massol J, Gatau-Pélanchon J, Blin D, Langlet F, Lévy S, Montiès J R, Gérard R

出版信息

Arch Mal Coeur Vaiss. 1985 Jan;78(1):103-10.

PMID:3919669
Abstract

Fifty-nine patients operated for Fallot's tetralogy were reviewed over 3 years after surgery. The average age at surgery was 7.4 years (range 6 months to 37 years). The review included ECG, chest X-ray, echocardiography, exercise stress testing and Holter monitoring, completed by cardiac catheterisation in 10 cases and electrophysiological investigation in 4 cases. Forty-eight of the 59 patients (81.3 p. 100) had no signs of ventricular arrhythmia or only benign ventricular extrasystoles (Group I). Four patients (6.8 p. 100) had severe ventricular arrhythmias (Group II). Seven patients (11.9 p. 100) had one or more episodes of ventricular tachycardia (VT) (Group III) and, in 3 of these patients, VT was recorded during Holter monitoring or exercise stress testing. One patient in Group III died after reoperation, but there were no cases of sudden death in this series. The high risk patients Groups II and III) were operated late (after 5 years), had bi- or trifascicular block (7 out of 11 cases), ventricular extrasystoles on resting ECGs (9 out of 11 cases), cardiomegaly (6 out of 7 cases in Group III), echocardiographic dilatation of the infundibulum (6 out of the 8 patients undergoing echocardiography in Groups II and III). They had significant residual malformation but without right ventricular hypertension (as judged mainly by immediate postoperative data). Ventricular arrhythmias occurred over 6 years after surgery. However, none of the patients operated before 2 years of age had ventricular arrhythmias or VT with a mean follow-up period of 7.5 years, perhaps because LV function was protected.(ABSTRACT TRUNCATED AT 250 WORDS)

摘要

对59例接受法洛四联症手术的患者进行了术后3年以上的随访。手术时的平均年龄为7.4岁(范围6个月至37岁)。随访内容包括心电图、胸部X线、超声心动图、运动负荷试验和动态心电图监测,10例患者进行了心导管检查,4例患者进行了电生理检查。59例患者中有48例(81.3%)无室性心律失常迹象或仅有良性室性早搏(I组)。4例患者(6.8%)有严重室性心律失常(II组)。7例患者(11.9%)有一次或多次室性心动过速(VT)发作(III组),其中3例患者在动态心电图监测或运动负荷试验中记录到VT。III组中有1例患者再次手术后死亡,但本系列中无猝死病例。高危患者(II组和III组)手术较晚(5岁以后),有双束支或三束支阻滞(11例中的7例),静息心电图有室性早搏(11例中的9例),心脏扩大(III组7例中的6例),超声心动图显示漏斗部扩张(II组和III组接受超声心动图检查的8例患者中的6例)。他们有明显的残余畸形,但无右心室高压(主要根据术后即刻数据判断)。室性心律失常发生在术后6年以上。然而,2岁前接受手术的患者中,平均随访7.5年,无室性心律失常或VT,可能是因为左心室功能得到了保护。(摘要截断于250字)

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