Vahanian A, Enriquez-Sarano M, Jais J M, Luxereau P, Frémont D, Charbel P, Kassab R, Savier C, Acar J
Arch Mal Coeur Vaiss. 1985 Jan;78(1):119-25.
36 patients with a total of 39 pericardial Ionescu-Shiley bioprostheses (20 aortic, 13 mitral and 3 double valve replacements) were studied. The population consisted if 12 women and 24 men with an average age of 33 +/- 11 years. The control was performed on average 7 +/- 4 months after surgery. At the time of investigation all patients were in functional classes I or II of the NYHA. The average cardio-thoracic ratio was 0.51 +/- 0.05. The catheter data showed a mean pulmonary capillary pressure of 10 +/- 2.7 mmHg, a mean cardiac index of 3.2 +/- 0.9 l/min/m2, a mean end diastolic volume of 132 +/- 33 ml/m2 and a mean ejection fraction of 0.53 +/- 0.12. Haemodynamic data was obtained under basal conditions and during intravenous infusion of isoproterenol. The average transvalvular pressure gradient was measured by transseptal catheterisation. The cardiac output was measured by dye dilution and the functional surface area calculated using the Gorlin formula (k = 44.5 for the aortic valve and k = 31 for the mitral valve). Perivalvular leaks were excluded by selective left ventriculography or aortography. The average transvalvular pressure gradients for the aortic valve prostheses (no 19 = 1, no 21 = 4, no 23 = 3, no 25 = 7, no 27 = 8) were 17 +/- 7 mmHg for no 19 and 21, 12 +/- 5 mmHg for no 23 and 25, and 9.7 +/- 2.7 mmHg for no 27.(ABSTRACT TRUNCATED AT 250 WORDS)
对36例患者共39个Ionescu-Shiley心包生物瓣（20个主动脉瓣、13个二尖瓣和3个双瓣置换）进行了研究。研究人群包括12名女性和24名男性，平均年龄33±11岁。平均在术后7±4个月进行对照检查。在调查时，所有患者的心功能分级均为纽约心脏协会（NYHA）I级或II级。平均心胸比率为0.51±0.05。导管检查数据显示，平均肺毛细血管压为10±2.7 mmHg，平均心脏指数为3.2±0.9 l/min/m²，平均舒张末期容积为132±33 ml/m²，平均射血分数为0.53±0.12。在基础状态下和静脉输注异丙肾上腺素期间获取血流动力学数据。通过经房间隔导管插入术测量平均跨瓣压差。通过染料稀释法测量心输出量，并使用Gorlin公式（主动脉瓣k = 44.5，二尖瓣k = 31）计算功能表面积。通过选择性左心室造影或主动脉造影排除瓣周漏。主动脉瓣人工瓣膜（19号= 1个，21号= 4个，23号= 3个，25号= 7个，27号= 8个）的平均跨瓣压差，19号和21号为17±7 mmHg，23号和25号为12±5 mmHg，27号为9.7±2.7 mmHg。（摘要截选至250字）
