Cashman J N, Jones R M, Foster J M, Adams A P
Br J Anaesth. 1985 Mar;57(3):255-8. doi: 10.1093/bja/57.3.255.
The effect of a constant i.v. infusion of lysine acetyl salicylate (LAS) on pain after operation was compared with that of a constant infusion of morphine in 30 patients undergoing unilateral inguinal herniorrhaphy. LAS provided analgesia equivalent to that provided by morphine and was associated with significantly less drowsiness, nausea and vomiting. No patient in either group was noted to suffer from respiratory depression. No untoward side effects were noted during or following the administration of LAS.
对30例接受单侧腹股沟疝修补术的患者,比较了持续静脉输注赖氨酸乙酰水杨酸酯(LAS)与持续输注吗啡对术后疼痛的影响。LAS提供的镇痛效果与吗啡相当,且嗜睡、恶心和呕吐明显较少。两组均未发现患者出现呼吸抑制。在给予LAS期间或之后未观察到不良副作用。