College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China.
College of Pharmacy, Hubei University of Chinese Medicine, Wuhan 430065, China; Center for Hubei TCM Processing Technology Engineering, Wuhan 430065, China; Hubei Shizhen Laboratory, Wuhan 430065, China.
Chin J Nat Med. 2024 Aug;22(8):756-768. doi: 10.1016/S1875-5364(24)60591-1.
Atractylodis Rhizoma, a traditional Chinese medicine with an extensive history of treating gastrointestinal disorders and other diseases, undergoes various processing methods in China to enhance its therapeutic efficacy for specific conditions. However, a comprehensive report detailing the changes in chemical composition and pharmacological effects due to these processing methods is currently lacking. This article provides a systematic review of the commonly employed processing techniques for Atractylodis Rhizoma, including raw Atractylodis Rhizoma (SCZ), bran-fried Atractylodis Rhizoma (FCZ), deep-fried Atractylodis Rhizoma (JCZ), and rice water-processed Atractylodis Rhizoma (MCZ). It examines the alterations in chemical constituents and pharmacological activities resulting from these processes and elucidates the mechanisms of action of the primary components in the various processed forms of Atractylodis Rhizoma in the treatment of gastrointestinal diseases.
苍术，一种具有悠久历史的中药，用于治疗胃肠道疾病和其他疾病，在中国经历了各种加工方法，以增强其对特定疾病的疗效。然而，目前缺乏一份全面的报告，详细说明这些加工方法导致的化学成分和药理作用的变化。本文系统地综述了苍术常用的加工技术，包括生苍术（SCZ）、麸炒苍术（FCZ）、焦苍术（JCZ）和米泔水制苍术（MCZ）。研究了这些过程导致的化学成分和药理活性的变化，并阐明了不同炮制形式的苍术中主要成分在治疗胃肠道疾病中的作用机制。
