Department of Urology, Weill Cornell Medicine, New York, NY, USA.
Department of Urology. Keck School of Medicine of USC, 1441 Eastlake Ave Suite 7416, Los Angeles, CA, 90089, USA.
Curr Urol Rep. 2024 Nov;25(11):277-285. doi: 10.1007/s11934-024-01223-7. Epub 2024 Aug 28.
This review paper summarizes the available literature on the evolution of surgical approach to radical cystectomy in female bladder cancer patients and its impact on functional outcomes in orthotopic neobladder.
Traditionally, radical cystectomy in female bladder cancer patients has been maximally extirpative with pelvic exenteration. Recently, new techniques which include pelvic organ-sparing, nerve-sparing and vaginal-sparing have demonstrated improved rates of urinary incontinence and retention. Additional techniques include prophylactic apical suspension which reduces the likelihood of pelvic organ prolapse, a risk factor for voiding dysfunction in the setting of orthotopic neobladder. Surgical management of bladder cancer in female patients has evolved to include surgical approaches which center quality of life and functional outcomes that are unique to female patients who have undergone radical cystectomy with ileal neobladder and can be optimized based on considerations regarding an approach that limits pelvic floor and pelvic nerve disruption.
本文总结了女性膀胱癌根治性膀胱切除术手术入路演变及其对原位新膀胱功能结局影响的相关文献。
传统上,女性膀胱癌根治性膀胱切除术采用最大范围的盆腔脏器切除术。最近,包括保留盆腔器官、保留神经和保留阴道的新技术显示出更高的尿失禁和保留率。其他技术包括预防性顶悬术,可降低盆腔器官脱垂的可能性,而盆腔器官脱垂是原位新膀胱排尿功能障碍的一个危险因素。女性膀胱癌的外科治疗方法已经发展到包括以生活质量和功能结局为中心的手术方法,这些方法是专为接受回肠新膀胱根治性膀胱切除术的女性患者设计的,可以根据限制盆底和盆神经损伤的手术方法进行优化。