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从无缝合到标准:腹腔镜部分肾切除术中转开放率的综合分析。

From sutureless to standard: a comprehensive analysis of conversion rates in laparoscopic partial nephrectomy.

机构信息

Department of Urology, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200011, China.

出版信息

BMC Urol. 2024 Aug 28;24(1):183. doi: 10.1186/s12894-024-01578-6.

DOI:10.1186/s12894-024-01578-6
PMID:39198764
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11351731/
Abstract

OBJECTIVE

To assess the rate at which sutureless partial nephrectomy (SLPN) transitions to standard partial nephrectomy (SPN), focusing on preoperative factors that might prompt such conversions.

PATIENTS AND METHODS

In this retrospective study, we analyzed the efficacy of SLPN performed on adults at our institution from 2016 to 2023. The subjects were patients diagnosed with localized solid renal tumors. The primary technique employed was resection with scissors and argon beam coagulation for hemostasis, with suturing techniques used only when necessary. Predictive factors necessitating conversion to SPN were identified, and the associations among multiple variables were explored using various statistical analysis methods, including logistic regression, to identify key preoperative predictive factors.

RESULTS

Our institution performed 353 SLPN, with 21 cases (5.9%) necessitating conversion to SPN. The conversion rates for the Laparoscopic Partial Nephrectomy (LPN) subgroup and the Robotic-assist Partial Nephrectomy (RPN) subgroup were 7.9% (17/215) and 2.9% (4/138), respectively, nearing statistical significance (P = .066). Significant differences were observed between the conversion group and the no conversion group in terms of preoperative estimated Glomerular Filtration Rate (eGFR), age at surgery, tumor size, and exophytic/endophytic characteristics. Multivariate analysis identified age at surgery, preoperative eGFR, radiological tumor size, and tumor exophytic/endophytic nature as significant predictors for conversion to SPN.

CONCLUSION

This investigation highlights the efficacy and feasibility of SLPN while identifying critical factors influencing the necessity for conversion to SPN. The identified predictors, including younger surgical age, superior preoperative eGFR, and specific tumor characteristics, provide valuable insights for refining surgical strategies.

摘要

目的

评估无缝合部分肾切除术 (SLPN) 转为标准部分肾切除术 (SPN) 的比率,重点关注可能促使此类转换的术前因素。

患者与方法

在这项回顾性研究中,我们分析了 2016 年至 2023 年在我们机构进行的成人 SLPN 的疗效。研究对象为诊断为局限性实体肾肿瘤的患者。主要技术是用剪刀和氩束凝固进行切除以止血,仅在必要时使用缝合技术。确定需要转为 SPN 的预测因素,并使用各种统计分析方法(包括逻辑回归)探索多个变量之间的关联,以确定关键的术前预测因素。

结果

我们机构进行了 353 例 SLPN,其中 21 例(5.9%)需要转为 SPN。腹腔镜部分肾切除术 (LPN) 亚组和机器人辅助部分肾切除术 (RPN) 亚组的转化率分别为 7.9%(17/215)和 2.9%(4/138),接近统计学意义 (P = .066)。在术前估算肾小球滤过率 (eGFR)、手术时年龄、肿瘤大小和外生性/内生性特征方面,转换组与未转换组之间存在显著差异。多变量分析确定手术时年龄、术前 eGFR、影像学肿瘤大小和肿瘤外生性/内生性特征是转为 SPN 的重要预测因素。

结论

本研究强调了 SLPN 的疗效和可行性,同时确定了影响转为 SPN 必要性的关键因素。确定的预测因素,包括较年轻的手术年龄、较好的术前 eGFR 和特定的肿瘤特征,为完善手术策略提供了有价值的见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d20/11351731/dc1ebc458ab0/12894_2024_1578_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d20/11351731/dc1ebc458ab0/12894_2024_1578_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9d20/11351731/dc1ebc458ab0/12894_2024_1578_Fig1_HTML.jpg

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本文引用的文献

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Resection Techniques During Robotic Partial Nephrectomy: A Systematic Review.机器人辅助部分肾切除术的切除技术:一项系统评价
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Perioperative, oncologic, and functional outcomes of robot-assisted partial nephrectomy for special types of renal tumors (hilar, endophytic, or cystic): an evidence-based analysis of comparative outcomes.
机器人辅助部分肾切除术治疗特殊类型肾肿瘤(肾门部、内生性或囊性)的围手术期、肿瘤学及功能结局:基于证据的比较结局分析
Front Oncol. 2023 Apr 20;13:1178592. doi: 10.3389/fonc.2023.1178592. eCollection 2023.
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Robotic Off-Clamp Simple Enucleation Single-Layer Renorrhaphy Partial Nephrectomy (ROSS): Surgical Insights after an Initial Experience.机器人辅助无阻断简单剜除单层肾缝合术部分肾切除术(ROSS):初步经验后的手术见解
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