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杜蒙羊早期生长性状遗传参数的估计

Estimation of Genetic Parameters of Early Growth Traits in Dumeng Sheep.

作者信息

Wang Ruijun, Wang Xinle, Liu Baodong, Zhang Lifei, Li Jing, Chen Dayong, Ma Yunhui, He Huijie, Liu Jie, Liu Yongbin, Zhang Yanjun

机构信息

College of Animal Science, Inner Mongolia Agricultural University, Hohhot 010018, China.

Inner Mongolia Sino Sheep Technology Co., Ltd., Ulanqab 011800, China.

出版信息

Animals (Basel). 2024 Aug 7;14(16):2298. doi: 10.3390/ani14162298.

Abstract

This study aimed to estimate the genetic and non-genetic factors that affect the nine early growth traits of Dumeng sheep, as well as to estimate the variance components and genetic parameters associated with these traits. A dataset containing detailed information on 17,896 preweaning trait records of 4474 lambs was collected. In addition, 5015 postweaning trait records of 1003 lambs were documented. The effects of recipient dam age, sex, year, season, and herd on the early growth traits were assessed using the general linear model procedure of the statistical analysis system, revealing different levels of significance across different traits. To determine the most suitable model for estimating the genetic parameters, the likelihood ratio (LR) test was employed, fitting six animal models that either excluded or included maternal genetic and maternal permanent environmental effects within the average information restricted maximum likelihood (AIREML) framework using WOMBAT software (Version: 23/11/23). The model incorporating direct additive genetic effects, maternal genetic effects, and maternal permanent environment effects as random effects (model 6) provided the best fit for birth weight (BW) estimation. In contrast, the model combining direct additive genetic effects and maternal permanent environment effects as random effects (model 2) demonstrated a superior fit for estimating the genetic parameters of weaning weight (WW), average daily gain weight from birth to weaning (ADG1), and Kleiber ratio from birth to weaning (KR1). With regard to the genetic parameters of body weight at 6 months of age (6MW), average daily gain weight from weaning to 6 months (ADG2), average daily gain weight from birth to 6 months (ADG3), Kleiber ratio from weaning to 6 months (KR2), and Kleiber ratio from birth to 6 months (KR3), model 1, which incorporates only direct additive genetic effects, was identified as the optimal choice. With the optimal model, the heritability estimates ranged from 0.010 ± 0.033 for 6MW to 0.1837 ± 0.096 for KR3. The bivariate analysis method was employed to estimate the correlation between various traits using the most suitable model. The absolute values of genetic correlation coefficients among the traits spanned a range from 0.1460 to 0.9998, highlighting both weak and strong relationships among the studied traits. Specifically, the estimated genetic correlations between WW and ADG1, ADG3, KR1, and KR3 were 0.9859, 0.9953, 0.9911, and 0.9951, respectively, while the corresponding phenotypic correlations were 0.9752, 0.7836, 0.8262, and 0.5767. These findings identified that WW could serve as an effective selection criterion for enhancing early growth traits.

摘要

本研究旨在估计影响杜蒙羊九个早期生长性状的遗传和非遗传因素,并估计与这些性状相关的方差成分和遗传参数。收集了一个数据集,其中包含4474只羔羊的17896条断奶前性状记录的详细信息。此外,还记录了1003只羔羊的5015条断奶后性状记录。使用统计分析系统的通用线性模型程序评估受体母羊年龄、性别、年份、季节和畜群对早期生长性状的影响,结果显示不同性状的显著水平不同。为了确定估计遗传参数的最合适模型,采用了似然比(LR)检验,在平均信息限制最大似然(AIREML)框架内,使用WOMBAT软件(版本:23/11/23)拟合了六个动物模型,这些模型要么排除要么包含母本遗传和母本永久环境效应。将直接加性遗传效应、母本遗传效应和母本永久环境效应作为随机效应的模型(模型6)最适合出生体重(BW)估计。相比之下,将直接加性遗传效应和母本永久环境效应作为随机效应的模型(模型2)在估计断奶体重(WW)、出生至断奶平均日增重(ADG1)和出生至断奶克莱伯比率(KR1)的遗传参数方面表现更优。对于6月龄体重(6MW)、断奶至6月龄平均日增重(ADG2)、出生至6月龄平均日增重(ADG3)、断奶至6月龄克莱伯比率(KR2)和出生至6月龄克莱伯比率(KR3)的遗传参数,仅包含直接加性遗传效应的模型1被确定为最佳选择。采用最优模型时,遗传力估计值范围从6MW的0.010±0.033到KR3的0.1837±0.096。采用双变量分析方法,使用最合适的模型估计各性状之间的相关性。性状间遗传相关系数的绝对值范围为0.1460至0.9998,突出了所研究性状之间既有弱关系也有强关系。具体而言,WW与ADG1、ADG3、KR1和KR3的估计遗传相关性分别为0.9859、0.9953、0.9911和0.9951,而相应的表型相关性分别为0.9752、0.7836、0.8262和0.5767。这些发现表明,WW可作为提高早期生长性状的有效选择标准。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ff67/11350660/b825a5043cda/animals-14-02298-g001.jpg

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