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使用定制钛植入物进行髋臼边缘扩展治疗犬髋关节发育不良一年后的结果

Outcome One Year after Acetabular Rim Extension Using a Customized Titanium Implant for Treating Hip Dysplasia in Dogs.

作者信息

Kwananocha Irin, Magré Joëll, Kamali Amir, Verseijden Femke, Willemsen Koen, Ji Yuntao, van der Wal Bart C H, Sakkers Ralph J B, Tryfonidou Marianna A, Meij Björn P

机构信息

Department of Clinical Sciences, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 1, 3584 CL Utrecht, The Netherlands.

Research and Academic Service, Faculty of Veterinary Medicine, Kasetsart University, 50 Ngamwongwan Rd., Lat Yao, Chatuchak, Bangkok 10900, Thailand.

出版信息

Animals (Basel). 2024 Aug 17;14(16):2385. doi: 10.3390/ani14162385.

Abstract

The acetabular rim extension (ACE-X) implant is a custom-made three-dimensionally printed titanium device designed for the treatment of canine hip dysplasia. In this study, 34 dogs (61 hips) underwent ACE-X implantation, and assessments were conducted using computed tomography, force plate analysis, Ortolani's test, and the Helsinki chronic pain index (HCPI) questionnaires at five intervals: the pre-operative day, the surgery day, and the 1.5-month, 3-month, and 12-month follow-ups. Statistically significant increases in femoral head coverage with a negative Ortolani subluxation test were observed immediately after surgery and persisted throughout the study. Osteoarthritis (OA) scores remained stable, but osteophyte size significantly increased between the surgery day and the 12-month follow-up, especially in hips with a baseline OA score of 2 compared to those with a score of 1. The force plate data showed no significant changes during the study. The HCPI demonstrated a significant decrease in pain score from pre-operative value to six-week follow-up and gradually decreased over time. Major complications were identified in six hips (9.8%) of four dogs. In conclusion, the ACE-X implant effectively increased femoral head coverage, eliminated subluxation, and provided long-term pain relief with minimal complications, benefiting over 90% of the study population. The study supports the ACE-X implant as a valuable alternative treatment for canine hip dysplasia.

摘要

髋臼边缘延伸(ACE-X)植入物是一种定制的三维打印钛制装置,设计用于治疗犬髋关节发育不良。在本研究中,34只犬(61个髋关节)接受了ACE-X植入,并在五个时间点使用计算机断层扫描、测力板分析、奥托拉尼试验和赫尔辛基慢性疼痛指数(HCPI)问卷进行评估:术前日、手术日以及术后1.5个月、3个月和12个月的随访。术后立即观察到股骨头覆盖度有统计学意义的增加,且奥托拉尼半脱位试验为阴性,并且在整个研究过程中持续存在。骨关节炎(OA)评分保持稳定,但在手术日至12个月随访期间骨赘大小显著增加,尤其是基线OA评分为2的髋关节与评分为1的髋关节相比。测力板数据在研究期间无显著变化。HCPI显示疼痛评分从术前值到六周随访时有显著下降,并随时间逐渐降低。在4只犬的6个髋关节(9.8%)中发现了主要并发症。总之,ACE-X植入物有效地增加了股骨头覆盖度,消除了半脱位,并以最小的并发症提供了长期疼痛缓解,使超过90%的研究对象受益。该研究支持ACE-X植入物作为犬髋关节发育不良的一种有价值的替代治疗方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b599/11350793/be117e729e6e/animals-14-02385-g001.jpg

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