Deprenyl selectively inhibits [3H]MPTP binding sites in monkey brain.
作者信息
Del Zompo M, Pintus S, Zuddas A, Corsini G U
出版信息
Eur J Pharmacol. 1985 Jan 2;107(2):285-6. doi: 10.1016/0014-2999(85)90073-1.
PMID:3920058
Abstract
摘要
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Deprenyl selectively inhibits [3H]MPTP binding sites in monkey brain.司来吉兰选择性抑制猴脑中的[3H]MPTP结合位点。
Eur J Pharmacol. 1985 Jan 2;107(2):285-6. doi: 10.1016/0014-2999(85)90073-1.
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Involvement of monoamine oxidase enzymes in the action of 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine, a selective neurotoxin, in the squirrel monkey: binding and biochemical studies.单胺氧化酶在选择性神经毒素1-甲基-4-苯基-1,2,5,6-四氢吡啶对松鼠猴的作用中的参与：结合与生化研究。
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Depletion of norepinephrine in mouse heart by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mimicked by 1-methyl-4-phenylpyridinium (MPP+) and not blocked by deprenyl.
Life Sci. 1986 Nov 3;39(18):1645-50. doi: 10.1016/0024-3205(86)90161-x.
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Deprenyl antagonizes acute lethality of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice.司来吉兰可拮抗1-甲基-4-苯基-1,2,3,6-四氢吡啶对小鼠的急性致死作用。
J Pharmacol Exp Ther. 1988 Nov;247(2):531-5.
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Deprenyl as prophylaxis against Parkinson's disease?司来吉兰作为帕金森病的预防药物？
Clin Neuropharmacol. 1988 Dec;11(6):500-11. doi: 10.1097/00002826-198812000-00003.
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L-deprenyl in prevention of MPTP induced depletion of striatal enkephalins in mice.左旋司来吉兰对预防小鼠中MPTP诱导的纹状体脑啡肽耗竭的作用
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Chronic L-deprenyl does not alter the restoration of striatal dopamine in MPTP-lesioned mice.
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Characterization of [3H]MPTP binding sites.[3H]MPTP结合位点的表征
Adv Neurol. 1987;45:153-8.
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Pargyline and deprenyl prevent the neurotoxicity of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) in monkeys.帕吉林和司来吉兰可预防1-甲基-4-苯基-1,2,3,6-四氢吡啶（MPTP）对猴子的神经毒性。
Eur J Pharmacol. 1984 Oct 30;106(1):209-10. doi: 10.1016/0014-2999(84)90700-3.
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In vivo labelling and axonal transport of monoamine oxidase in the rat basal ganglia using radioactive pargyline.使用放射性异炔酰苯在大鼠基底神经节中对单胺氧化酶进行体内标记和轴突运输。
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