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关于牙齿异常与化疗之间关联的叙述性综述

A Narrative Review of the Association between Dental Abnormalities and Chemotherapy.

作者信息

Akitomo Tatsuya, Tsuge Yasuko, Mitsuhata Chieko, Nomura Ryota

机构信息

Department of Pediatric Dentistry, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima 734-8553, Japan.

出版信息

J Clin Med. 2024 Aug 22;13(16):4942. doi: 10.3390/jcm13164942.

Abstract

Dental abnormalities are often detected in childhood and are reported to occur with high prevalence in patients who have undergone cancer treatment or chemotherapy. We performed a literature search of PubMed from 2004 to 2024 using the terms "dental anomaly" and "panoramic examination", and 298 potentially relevant articles were found. Thirty-one articles about dental abnormalities matched the eligibility criteria and were extracted for this review. Although the prevalence of tooth agenesis and microdontia in the general population was reported to be approximately 10% and 3%, respectively, the prevalence in patients who had undergone cancer treatment or chemotherapy was higher in all surveys, suggesting that the treatment is related to the occurrence of dental abnormalities. It is important to continue long-term follow-up with patients not only during treatment but also after the completion of treatment. Dental professionals should provide information about dental abnormalities to patients, their guardians, and medical professionals, which may lead to improvement in the quality of life of patients.

摘要

牙齿异常常在儿童期被发现,据报道,在接受过癌症治疗或化疗的患者中,其发生率很高。我们使用“牙齿异常”和“全景检查”这两个术语,在2004年至2024年期间对PubMed进行了文献检索,共找到298篇可能相关的文章。31篇关于牙齿异常的文章符合纳入标准,被提取用于本综述。尽管据报道,一般人群中牙齿缺失和过小牙的发生率分别约为10%和3%,但在所有调查中,接受过癌症治疗或化疗的患者中的发生率更高,这表明该治疗与牙齿异常的发生有关。不仅在治疗期间,而且在治疗完成后,对患者进行长期随访都很重要。牙科专业人员应向患者、其监护人及医疗专业人员提供有关牙齿异常的信息,这可能会改善患者的生活质量。

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