Talekar Abhinav Liladhar, Musale Prasad K, Kothare Sneha Sunil
Department of Pediatric and Preventive Dentistry, M. A. Rangoonwala College of Dental Sciences & Research Centre, Pune, Maharashtra, India.
Int J Clin Pediatr Dent. 2022 Jul-Aug;15(4):428-432. doi: 10.5005/jp-journals-10005-2417.
The study aims to evaluate the prevalence of dental caries and anomalies in pediatric patients undergoing chemotherapy or those who have completed chemotherapy.
A total of 250 pediatric patients within the age group of 6 months to 17 years, either admitted to hospitals for chemotherapy or on follow-up, were included as a part of the study. Complete oral examination inclusive of the diet history, oral hygiene methods, past dental history, the decayed, missing, and filled teeth (DMFT), def score, and any dental anomaly was diagnosed clinically and radiographically using an orthopantomogram. The samples were further categorized under type of malignancies and duration of chemotherapeutic drug usage groups (from 6 months to 10 years and more than 10 years) to establish a correlation of these variables with the prevalence of dental caries and dental anomalies.
Among all patients, 108 (43.2%) had completed the treatment (chemotherapy), while 142 (56.8%) were undergoing the treatment. Forty-three (17.2%) patients showed positive findings for dental anomalies.
The present study confirms the strong positive correlation between long-term exposure to chemotherapeutic agents and the prevalence of dental anomalies and dental caries in children.
Talekar AL, Musale PK, Kothare SS. Dental Caries and Dental Anomalies in Children Undergoing Chemotherapy for Malignant Diseases. Int J Clin Pediatr Dent 2022;15(4):428-432.
本研究旨在评估接受化疗或已完成化疗的儿科患者中龋齿和牙齿异常的患病率。
共有250名年龄在6个月至17岁之间的儿科患者纳入本研究，这些患者要么因化疗入院，要么处于随访中。进行全面的口腔检查，包括饮食史、口腔卫生方法、既往牙科病史、龋失补牙数（DMFT）、def评分，并通过口腔全景片进行临床和影像学诊断，以确定任何牙齿异常情况。样本进一步根据恶性肿瘤类型和化疗药物使用时长分组（6个月至10年以及超过10年），以建立这些变量与龋齿和牙齿异常患病率之间的相关性。
在所有患者中，108例（43.2%）已完成治疗（化疗），而142例（56.8%）正在接受治疗。43例（17.2%）患者牙齿异常检查结果呈阳性。
本研究证实长期接触化疗药物与儿童牙齿异常和龋齿患病率之间存在强正相关。
Talekar AL, Musale PK, Kothare SS. 恶性疾病化疗儿童的龋齿和牙齿异常。《国际临床儿科牙科学杂志》2022；15(4):428 - 432。
