Amiri Sohrab, Mahmood Nailah, Yusuf Rahemeen, Ghenimi Nadirah, Javaid Syed Fahad, Khan Moien Ab
Medicine, Quran and Hadith Research Center, Baqiyatallah University of Medical Sciences, Tehran 17166, Iran.
Division of Health Research, Lancaster University, Lancaster LA1 4YW, UK.
Children (Basel). 2024 Aug 20;11(8):1015. doi: 10.3390/children11081015.
(1) Objectives: The impact of abnormal body mass index (BMI) on health is extensive, and various risk factors contribute to its effects. This study aimed to examine the association between adverse childhood experiences (ACEs) and BMI categories, including underweight, overweight, obesity, severe obesity, and morbid obesity; (2) Methods: Three databases were searched: Web of Science, PubMed, and Scopus. Manual searches were conducted using Google Scholar and ResearchGate. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to assess the association between ACEs and BMI. A random-effects model was used to combine the ORs and CIs across studies; (3) Results: This meta-analysis included 71 studies. The pooled ORs for the relationship between ACEs and obesity was 1.42 (95% CI: 1.24-1.63, Z = 4.96, < 0.001), indicating a significant association. ACEs showed a positive association with overweight (OR = 1.16, 95% CI: 1.06-1.27, Z = 3.24, = 0.001). Specifically, ACEs ≥ 4 were strongly associated with obesity (OR = 2.06, 95% CI: 1.27-3.36, Z = 2.90, = 0.004). Sexual abuse was also found to be significantly associated with obesity (OR = 1.46, 95% CI: 1.29-1.65, Z = 5.98, < 0.001); (4) Conclusion: This study finds that individuals who have experienced ACEs are more likely to have a higher BMI in adulthood. Therefore, ACEs should be considered a factor associated with abnormal BMI.
(1) 目的：异常体重指数（BMI）对健康的影响广泛，多种风险因素导致其产生影响。本研究旨在探讨不良童年经历（ACEs）与BMI类别之间的关联，包括体重过轻、超重、肥胖、重度肥胖和病态肥胖；(2) 方法：检索了三个数据库：科学网、PubMed和Scopus。使用谷歌学术和ResearchGate进行手动检索。计算优势比（ORs）和95%置信区间（CIs）以评估ACEs与BMI之间的关联。采用随机效应模型合并各研究的ORs和CIs；(3) 结果：该荟萃分析纳入了71项研究。ACEs与肥胖之间关系的合并OR为1.42（95%CI：1.24 - 1.63，Z = 4.96，P < 0.001），表明存在显著关联。ACEs与超重呈正相关（OR = 1.16，95%CI：1.06 - 1.27，Z = 3.24，P = 0.001）。具体而言，ACEs≥4与肥胖密切相关（OR = 2.06，95%CI：1.27 - 3.36，Z = 2.90，P = 0.004）。还发现性虐待与肥胖显著相关（OR = 1.46，95%CI：1.29 - 1.65，Z = 5.98，P < 0.001）；(4) 结论：本研究发现，经历过ACEs的个体成年后更有可能具有较高的BMI。因此，ACEs应被视为与异常BMI相关的一个因素。
