Laboratory of Genetics and Plant Breeding, Faculty of Agriculture, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Genes (Basel). 2024 Aug 1;15(8):1014. doi: 10.3390/genes15081014.
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) technologies have revolutionized genome editing, significantly advancing the improvement of cultivated crop species. This review provides an overview of genome-edited crops that have either reached the market or received the necessary approvals but are not yet available to consumers. We analyze various genome-editing studies to understand the distribution of different genome-editing systems, the types of site-directed nucleases employed, and the geographical spread of these studies, with a specific focus on global and European contexts. Additionally, we examine the target crops involved. The review also outlines the multiple steps required for the legal acceptance of genome-edited crops within European jurisdictions. We conclude with suggestions for the future prospects of genome-editing research in Europe, aiming to streamline the approval process and enhance the development and adoption of genome-edited crops.
簇状规律间隔短回文重复序列（CRISPR）技术彻底改变了基因组编辑，显著推动了栽培作物品种的改良。本综述概述了已经进入市场或获得必要批准但尚未面向消费者的基因编辑作物。我们分析了各种基因组编辑研究，以了解不同基因组编辑系统的分布、使用的定点核酸酶的类型以及这些研究的地理分布情况，重点关注全球和欧洲的情况。此外，我们还研究了涉及的目标作物。本综述还概述了在欧洲司法管辖区内对基因编辑作物进行法律认可所需的多个步骤。最后，我们对欧洲基因编辑研究的未来前景提出了建议，旨在简化审批流程并促进基因编辑作物的开发和采用。
