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危重症患者输血的当代研究综述。

A Contemporary Review of Blood Transfusion in Critically Ill Patients.

机构信息

Department of Hospital Internal Medicine, Mayo Clinic Health System, 1025 Marsh Street, Mankato, MN 56001, USA.

Department of Internal Medicine, Trinity Health Oakland/Wayne State University, Pontiac, MI 48341, USA.

出版信息

Medicina (Kaunas). 2024 Jul 31;60(8):1247. doi: 10.3390/medicina60081247.

Abstract

Blood transfusion is a common therapeutic intervention in hospitalized patients. There are numerous indications for transfusion, including anemia and coagulopathy with deficiency of single or multiple coagulation components such as platelets or coagulation factors. Nevertheless, the practice of transfusion in critically ill patients has been controversial mainly due to a lack of evidence and the need to consider the appropriate clinical context for transfusion. Further, transfusion carries many risk factors that must be balanced with benefits. Therefore, transfusion practice in ICU patients has constantly evolved, and we endeavor to present a contemporary review of transfusion practices in this population guided by clinical trials and expert guidelines.

摘要

输血是住院患者中常见的治疗干预措施。输血的适应证很多,包括贫血和凝血功能障碍,伴有单一或多种凝血成分(如血小板或凝血因子)的缺乏。然而,由于缺乏证据以及需要考虑输血的适当临床背景,危重症患者的输血实践一直存在争议。此外,输血有许多风险因素,必须与收益相平衡。因此,ICU 患者的输血实践一直在不断发展,我们努力根据临床试验和专家指南,对该人群的输血实践进行当代综述。

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