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新冠病毒感染后阻塞性睡眠呼吸暂停:一项观察性研究。

Obstructive Sleep Apnea after COVID-19: An Observational Study.

作者信息

Popovici George-Cosmin, Georgescu Costinela-Valerica, Vasile Mihaela-Camelia, Vlase Constantin-Marinel, Arbune Anca-Adriana, Arbune Manuela

机构信息

School for Doctoral Studies in Biomedical Sciences, "Dunarea de Jos" University from Galati, 800008 Galati, Romania.

Pneumophtiziology Hospital Galati, 800189 Galati, Romania.

出版信息

Life (Basel). 2024 Aug 22;14(8):1052. doi: 10.3390/life14081052.

Abstract

The risk factors of hospitalized COVID-19 and obstructive sleep apnea (OSA) overlap. The aim of this study is to evaluate the prevalence and associated factors of post-COVID-19 OSA in hospitalized adult patients from southeastern Romania. A follow-up study was conducted on patients hospitalized for COVID-19 at the Pneumology Hospital in Galati, Romania, between 2021 and 2022. OSA was evaluated using the Epworth and STOP-BANG questionnaires and nocturnal polygraphy monitoring. Out of 331 patients, 257 were evaluated for sleep apnea in the 12th week. The prevalence of severe OSA was 57.97%. Significant associations were found with male gender, an age over 60, obesity, and cardiovascular co-morbidities. Non-invasive ventilatory therapy (NIV) and a hygienic-dietary regimen were recommended based on severity following a control visit after a month. Developing strategies for diagnosing and monitoring sleep disorders, including home sleep apnea tests and patient education, are the next directions for post-COVID-19 management.

摘要

新型冠状病毒肺炎(COVID-19)住院患者与阻塞性睡眠呼吸暂停(OSA)的风险因素存在重叠。本研究旨在评估罗马尼亚东南部住院成年COVID-19患者感染后发生OSA的患病率及相关因素。对2021年至2022年期间在罗马尼亚加拉茨肺病医院因COVID-19住院的患者进行了一项随访研究。使用爱泼沃斯(Epworth)问卷、STOP-BANG问卷及夜间多导睡眠图监测来评估OSA。331例患者中,257例在第12周接受了睡眠呼吸暂停评估。重度OSA的患病率为57.97%。研究发现,重度OSA与男性、年龄超过60岁、肥胖及心血管合并症显著相关。在一个月后的复诊中,根据严重程度建议进行无创通气治疗(NIV)和卫生饮食方案。制定包括家庭睡眠呼吸暂停检测和患者教育在内的睡眠障碍诊断和监测策略,是COVID-19感染后管理的下一步方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eae5/11355273/e3a86de39631/life-14-01052-g0A1.jpg

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