Kiss László, Li Heng, Yan Hui, Kunsági-Máté Sándor
Institute of Organic and Medicinal Chemistry, Faculty of Pharmacy, University of Pécs, Honvéd útja 1, H-7624 Pécs, Hungary.
János Szentágothai Research Center, Ifjúság útja 20, H-7624 Pécs, Hungary.
Molecules. 2024 Aug 22;29(16):3972. doi: 10.3390/molecules29163972.
In the first part of this study, the electrochemical polymerization of two compounds, 3,5-dihydroxybenzoic acid and 2',6'-dihydroxyacetophenone, was compared in dimethyl sulfoxide solvent on platinum and glassy carbon electrodes. The voltammograms obtained showed remarkable differences between the two monomers and between the two electrode materials. The acetophenone derivative formed electropolymer remnants at the electrodes, while in the case of the benzoic acid derivative, practically no passivation occurred, and the scanning electron microscopic results reinforced this. A few stackings adsorbed only after electropolymerization from a highly concentrated solution of dihydroxybenzoic acid. As a modifying layer on the platinum and glassy carbon electrodes, the prepared films from 2',6'-dihydroxyacetophenone were tested for tributylamine in acetonitrile and in an aqueous solution of a redox-active compound, hydroquinone, during the stirring of the solution. More stable amperometric current signals could be reached with modified platinum than with glassy carbon, and the significant influence of the organic washing liquid after deposition was established via the study of noise level. In this respect, acetone was the best choice. The amperometric signals with the modified platinum obtained upon the addition of aliquots of the stock solution resulted in a 3.29 μM detection limit.
在本研究的第一部分中，比较了3,5 - 二羟基苯甲酸和2',6' - 二羟基苯乙酮这两种化合物在二甲基亚砜溶剂中于铂电极和玻碳电极上的电化学聚合。所得伏安图显示，这两种单体之间以及两种电极材料之间存在显著差异。苯乙酮衍生物在电极上形成了电聚合残余物，而对于苯甲酸衍生物，几乎没有发生钝化现象，扫描电子显微镜结果也证实了这一点。只有从高浓度的二羟基苯甲酸溶液中进行电聚合后，才吸附了少量堆叠物。作为铂电极和玻碳电极上的修饰层，对由2',6' - 二羟基苯乙酮制备的薄膜在乙腈和氧化还原活性化合物对苯二酚的水溶液中搅拌时检测三丁胺的性能进行了测试。与玻碳电极相比，修饰后的铂电极能获得更稳定的安培电流信号，并且通过对噪声水平的研究确定了沉积后有机洗涤液的显著影响。在这方面，丙酮是最佳选择。加入储备溶液等分试样后，修饰铂电极获得的安培信号产生了3.29 μM的检测限。
