Nutritional Support, Intestinal Rehabilitation and Intestinal Transplant Unit, Hospital Universitario Fundación Favaloro, Buenos Aires C1093AAS, Argentina.
Nutrients. 2024 Aug 10;16(16):2648. doi: 10.3390/nu16162648.
Chronic intestinal failure (CIF) is a heterogeneous disease that affects pediatric and adult populations worldwide and requires complex multidisciplinary management. In recent years, many advances in intravenous supplementation support, surgical techniques, pharmacological management, and intestinal transplants have been published. Based on these advances, international societies have published multiple recommendations and guidelines for the management of these patients. The purpose of this paper is to show the differences that currently exist between the recommendations (ideal life) and the experiences published by different programs around the world.
A review of the literature in PubMed from 1980 to 2024 was carried out using the following terms: intestinal failure, CIF, home parenteral nutrition, short bowel syndrome, chronic intestinal pseudo-obstruction, intestinal transplant, enterohormones, and glucagon-like peptide-2.
There is a difference between what is recommended in the guidelines and consensus and what is applied in real life. Most of the world's countries are not able to offer all of the steps needed to treat this pathology. The development of cooperative networks between countries is necessary to ensure access to comprehensive treatment for most patients on all continents, but especially in low-income countries.
慢性肠衰竭（CIF）是一种影响全球儿科和成人人群的异质性疾病，需要复杂的多学科管理。近年来，静脉补充支持、手术技术、药物管理和肠移植方面有许多进展已经发表。基于这些进展，国际社会已经发布了多项关于这些患者管理的建议和指南。本文旨在展示目前在推荐意见（理想生活）和世界各地不同计划发表的经验之间存在的差异。
使用以下术语在 PubMed 上对 1980 年至 2024 年的文献进行了回顾：肠衰竭、CIF、家庭肠外营养、短肠综合征、慢性假性肠梗阻、肠移植、肠激素和胰高血糖素样肽-2。
指南和共识中推荐的内容与实际应用之间存在差异。世界上大多数国家都无法提供治疗这种病理所需的所有步骤。有必要在国家之间发展合作网络，以确保大多数患者在各大洲，特别是在低收入国家获得全面治疗。
