• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

高粱中的蜀黍氰苷:生物合成、调控、生物学功能及对动物生产的挑战

Dhurrin in Sorghum: Biosynthesis, Regulation, Biological Function and Challenges for Animal Production.

作者信息

Wang Bo, Xiong Wangdan, Guo Yanjun

机构信息

Qingdao Key Laboratory of Specialty Plant Germplasm Innovation and Utilization in Saline Soils of Coastal Beach, Qingdao Agricultural University, Qingdao 266109, China.

Key Laboratory of National Forestry and Grassland Administration on Grassland Resources and Ecology in the Yellow River Delta, Qingdao Agricultural University, Qingdao 266109, China.

出版信息

Plants (Basel). 2024 Aug 17;13(16):2291. doi: 10.3390/plants13162291.

DOI:10.3390/plants13162291
PMID:39204727
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11359004/
Abstract

Sorghum () holds a significant position as the fifth most vital cereal crop globally. Its drought resistance and robust biomass production, coupled with commendable nutritional value, make sorghum a promising choice for animal feed. Nevertheless, the utilization of sorghum in animal production faces hurdles of dhurrin (a cyanogenic glycoside) poisoning. While dhurrin serves as a protective secondary metabolite during sorghum growth, the resulting highly toxic hydrogen cyanide poses a significant threat to animal safety. This review extensively examines the biometabolic processes of dhurrin, the pivotal genes involved in the regulation of dhurrin biosynthesis, and the factors influencing dhurrin content in sorghum. It delves into the impact of dhurrin on animal production and explores measures to mitigate its content, aiming to provide insights for advancing research on dhurrin metabolism regulation in sorghum and its rational utilization in animal production.

摘要

高粱()作为全球第五重要的谷类作物,占据着重要地位。其抗旱性和强大的生物量生产能力,再加上可观的营养价值,使高粱成为动物饲料的一个有前景的选择。然而,高粱在动物生产中的利用面临着羟基腈苷(一种含氰糖苷)中毒的障碍。虽然羟基腈苷在高粱生长过程中作为一种保护性次生代谢产物,但由此产生的剧毒氰化氢对动物安全构成重大威胁。本综述广泛研究了羟基腈苷的生物代谢过程、参与羟基腈苷生物合成调控的关键基因以及影响高粱中羟基腈苷含量的因素。它深入探讨了羟基腈苷对动物生产的影响,并探索降低其含量的措施,旨在为推进高粱中羟基腈苷代谢调控及其在动物生产中的合理利用研究提供见解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/c5255fe27034/plants-13-02291-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/129e4b868975/plants-13-02291-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/437cdf0b141d/plants-13-02291-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/999271e636ce/plants-13-02291-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/c5255fe27034/plants-13-02291-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/129e4b868975/plants-13-02291-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/437cdf0b141d/plants-13-02291-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/999271e636ce/plants-13-02291-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b30a/11359004/c5255fe27034/plants-13-02291-g004.jpg

相似文献

1
Dhurrin in Sorghum: Biosynthesis, Regulation, Biological Function and Challenges for Animal Production.高粱中的蜀黍氰苷:生物合成、调控、生物学功能及对动物生产的挑战
Plants (Basel). 2024 Aug 17;13(16):2291. doi: 10.3390/plants13162291.
2
Dhurrin increases but does not mitigate oxidative stress in droughted Sorghum bicolor.干旱胁迫下,德雷尔(Dhurrin)增加而非减轻高粱的氧化应激。
Planta. 2022 Feb 28;255(4):74. doi: 10.1007/s00425-022-03844-z.
3
Effects of PEG-induced osmotic stress on growth and dhurrin levels of forage sorghum.聚乙二醇诱导的渗透胁迫对饲料高粱生长和玉米朊水平的影响。
Plant Physiol Biochem. 2013 Dec;73:83-92. doi: 10.1016/j.plaphy.2013.09.001. Epub 2013 Sep 18.
4
Down-Regulation of Gene Through Antisense Approach Reduced the Cyanogenic Glycoside Dhurrin in [ (L.) Moench] to Improve Fodder Quality.通过反义技术下调基因表达降低了[(L.)Moench]中的氰基糖苷百脉根苷,从而提高了饲料质量。
Front Nutr. 2019 Aug 30;6:122. doi: 10.3389/fnut.2019.00122. eCollection 2019.
5
Prediction of Dhurrin Metabolism by Transcriptome and Metabolome Analyses in .通过转录组和代谢组分析预测高粱中蜀黍苷的代谢
Plants (Basel). 2020 Oct 19;9(10):1390. doi: 10.3390/plants9101390.
6
A combined biochemical screen and TILLING approach identifies mutations in Sorghum bicolor L. Moench resulting in acyanogenic forage production.联合生物化学筛选和 TILLING 方法鉴定导致高粱产生氰化饲料的突变。
Plant Biotechnol J. 2012 Jan;10(1):54-66. doi: 10.1111/j.1467-7652.2011.00646.x. Epub 2011 Aug 31.
7
Dhurrin metabolism in the developing grain of Sorghum bicolor (L.) Moench investigated by metabolite profiling and novel clustering analyses of time-resolved transcriptomic data.通过代谢物谱分析和时间分辨转录组数据的新型聚类分析研究双色高粱(L.)Moench发育籽粒中的羟基腈代谢。
BMC Genomics. 2016 Dec 13;17(1):1021. doi: 10.1186/s12864-016-3360-4.
8
Variation in production of cyanogenic glucosides during early plant development: A comparison of wild and domesticated sorghum.在植物早期发育过程中氰苷葡萄糖苷的产生变化:野生高粱和栽培高粱的比较。
Phytochemistry. 2021 Apr;184:112645. doi: 10.1016/j.phytochem.2020.112645. Epub 2021 Jan 19.
9
Regulation of dhurrin pathway gene expression during Sorghum bicolor development.高粱发育过程中硫苷途径基因表达的调控。
Planta. 2021 Nov 11;254(6):119. doi: 10.1007/s00425-021-03774-2.
10
Cyanogenesis in the Genus: From Genotype to Phenotype.氰苷的产生:从基因型到表型。
Genes (Basel). 2022 Jan 14;13(1):140. doi: 10.3390/genes13010140.

引用本文的文献

1
Genotype × Environment Effects in Three Wild Relatives of Sorghum From Australia.澳大利亚三种高粱野生近缘种的基因型×环境效应
Plant Environ Interact. 2025 Jun 6;6(3):e70065. doi: 10.1002/pei3.70065. eCollection 2025 Jun.
2
Unveiling the Potential Role of Dhurrin in Sorghum During Infection by the Head Smut Pathogen f. sp. .揭示高粱醛在高粱丝黑穗病菌侵染过程中的潜在作用 。(注:原文中“f. sp.”后面似乎内容不完整)
Plants (Basel). 2025 Feb 28;14(5):740. doi: 10.3390/plants14050740.
3
Release of Hypoglycin A from Hypoglycin B and Decrease of Hypoglycin A and Methylene Cyclopropyl Glycine Concentrations in Ruminal Fluid Batch Cultures.

本文引用的文献

1
The Putative GATA Transcription Factor GATA22 as a Novel Regulator of Dhurrin Biosynthesis.假定的GATA转录因子GATA22作为苦杏仁苷生物合成的新型调节因子。
Life (Basel). 2024 Apr 3;14(4):470. doi: 10.3390/life14040470.
2
Deciphering the Genetic Mechanisms of Salt Tolerance in L.: Key Genes and SNP Associations from Comparative Transcriptomic Analyses.解析L.中耐盐性的遗传机制:来自比较转录组分析的关键基因和单核苷酸多态性关联
Plants (Basel). 2023 Jul 13;12(14):2639. doi: 10.3390/plants12142639.
3
Wounding and methyl jasmonate increase cyanogenic glucoside concentrations in Sorghum bicolor via upregulation of biosynthesis.
瘤胃液分批培养中从降糖氨酸B释放出降糖氨酸A以及降糖氨酸A和亚甲基环丙基甘氨酸浓度的降低
Toxins (Basel). 2025 Jan 21;17(2):46. doi: 10.3390/toxins17020046.
伤口和茉莉酸甲酯通过上调生物合成增加了高粱中的氰基糖苷浓度。
Plant Biol (Stuttg). 2023 Jun;25(4):498-508. doi: 10.1111/plb.13522. Epub 2023 May 5.
4
Effects of on cyanogenic glycosides removal and fermentation qualities of ratooning sorghum.[具体物质]对宿根高粱中氰苷去除及发酵品质的影响
Front Microbiol. 2023 Feb 20;14:1128057. doi: 10.3389/fmicb.2023.1128057. eCollection 2023.
5
Whole-genome analysis guided molecular mechanism of cyanogenic glucoside degradation by yeast isolated from Prunus mume fruit syrup.从青梅果糖浆中分离出的酵母对氰苷葡萄糖苷降解的全基因组分析指导的分子机制。
Chemosphere. 2022 Nov;307(Pt 4):136061. doi: 10.1016/j.chemosphere.2022.136061. Epub 2022 Aug 14.
6
Effect of Urea Coated with Polyaspartic Acid on the Yield and Nitrogen Use Efficiency of Sorghum (, (L.) Moench.).聚天冬氨酸包膜尿素对高粱((L.) Moench.)产量及氮素利用效率的影响
Plants (Basel). 2022 Jun 29;11(13):1724. doi: 10.3390/plants11131724.
7
Regulation of cyanogenic glucosides in wild and domesticated Eusorghum taxa.野生和驯化的 Eusorghum 分类群中氰苷的调控。
Plant Biol (Stuttg). 2022 Oct;24(6):1084-1088. doi: 10.1111/plb.13447. Epub 2022 Jun 30.
8
Transcript profiles of wild and domesticated sorghum under water-stressed conditions and the differential impact on dhurrin metabolism.水胁迫条件下野生和栽培高粱的转录谱及其对狗尾草素代谢的差异影响。
Planta. 2022 Jan 27;255(2):51. doi: 10.1007/s00425-022-03831-4.
9
MeJA-responsive bHLH transcription factor LjbHLH7 regulates cyanogenic glucoside biosynthesis in Lotus japonicus.茉莉酸响应的 bHLH 转录因子 LjbHLH7 调控菜豆氰苷生物合成。
J Exp Bot. 2022 Apr 18;73(8):2650-2665. doi: 10.1093/jxb/erac026.
10
Cyanogenesis in the Genus: From Genotype to Phenotype.氰苷的产生:从基因型到表型。
Genes (Basel). 2022 Jan 14;13(1):140. doi: 10.3390/genes13010140.