心肌梗死患者 NT-proBNP 水平与现有/ QRS 碎裂的关系。
Relationship between NT-proBNP levels and existing/ QRS fragmentation in patients with myocardial infarction.
机构信息
Department of Cardiology, University of Health Science, Etlik City Hospital, Ankara, Türkiye.
Department of Cardiology, Eskisehir Osmangazi University, Eskişehir, Türkiye.
出版信息
Biomark Med. 2024;18(10-12):535-544. doi: 10.1080/17520363.2024.2345584. Epub 2024 May 24.
to assess the evolution of fragmented QRS (fQRS) and NT-proBNP levels during myocardial infarction (MI). Among 511 patients, 205 (40.1%) had fQRS, with 54 (26.3%) developing de novo fragmentation during hospitalization. NT-proBNP levels were significantly higher in the fQRS+ group compared with the fQRS- group (1555 vs. 796 pg/ml, p < 0.001). NT-proBNP levels were higher in patients with de novo fragmentation than in those without (2852 vs. 1370 pg/ml, p = 0.011). The incidence of major adverse cardiovascular events was notably higher in fQRS+ patients compared with fQRS- patients (p = 0.001). In acute MI, there was a significant association between fQRS and NT-proBNP levels, with higher NT-proBNP levels observed in those with de novo fQRS compared with those without.
评估心肌梗死（MI）期间碎裂 QRS 波（fQRS）和 NT-proBNP 水平的演变。在 511 例患者中，205 例（40.1%）存在 fQRS，其中 54 例（26.3%）在住院期间出现新出现的碎裂。与 fQRS- 组相比，fQRS+ 组的 NT-proBNP 水平显著更高（1555 与 796 pg/ml，p < 0.001）。与无新出现碎裂的患者相比，出现新出现碎裂的患者的 NT-proBNP 水平更高（2852 与 1370 pg/ml，p = 0.011）。与 fQRS- 患者相比，fQRS+ 患者的主要不良心血管事件发生率显著更高（p = 0.001）。在急性 MI 中，fQRS 与 NT-proBNP 水平之间存在显著相关性，与无新出现碎裂的患者相比，出现新出现碎裂的患者的 NT-proBNP 水平更高。
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