Bar Ilan University, Faculty of Engineering, Ramat Gan, Israel.
Bar Ilan University, The Institute of Nanotechnology and Advanced Materials, Ramat Gan, Israel.
J Biomed Opt. 2024 Aug;29(8):087001. doi: 10.1117/1.JBO.29.8.087001. Epub 2024 Aug 28.
A better understanding of diffusion reflection (DR) behavior may allow it to be used for more noninvasive applications, including the development of non-damaging techniques, especially for medical topical diagnosis and treatments.
For a bilayer opaque substance where the attenuation of the upper layer is larger than the attenuation of the lower layer, the DR crossover point ( ) is location where the photons coming from the bottom layer start affecting the DR. We aim to study the dependency of the on absorption changes in different layers for constant scattering and top layer thickness.
Monolayer and bilayer optical tissue-like phantoms were prepared and measured using a DR system. The results were compared with Monte Carlo simulations.
There is an agreement between the experiments and the simulations. correlates with the square root of the absorption coefficient ratio of the lower layer to the top layer.
The experimental findings support and validate the theoretical prediction describing the dependency of the on the square root of the ratio of the layers' absorption coefficients. In addition, a secondary breaking point is suggested to be observed experimentally at the entrance to the noise area.
更深入地理解扩散反射（DR）行为可能使其能够应用于更多非侵入性的应用，包括开发非破坏性技术，特别是在医学局部诊断和治疗方面。
对于上覆层衰减大于下覆层衰减的双层不透明物质，DR 交叉点（ ）是来自下覆层的光子开始影响 DR 的位置。我们的目的是研究在恒定散射和顶层厚度的情况下，不同层的吸收变化对 的依赖性。
使用 DR 系统制备单层和双层光学类似组织体模，并进行测量。将结果与蒙特卡罗模拟进行比较。
实验结果与模拟结果相符。 与下覆层与顶层吸收系数之比的平方根相关。
实验结果支持并验证了描述 与各层吸收系数之比的平方根的依赖性的理论预测。此外，建议在噪声区域入口处观察到一个二级转折点。
