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[F]FDG PET/CT对颅骨巨细胞动脉炎的可视化:一例报告

Visualization of cranial giant cell arteritis with [F]FDG PET/CT: A case report.

作者信息

Amjadeen Muhammed Sarjoon, Bhatt Manoj, Arnfield Evyn

机构信息

Department of Nuclear Medicine and Specialised PET Services, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia.

出版信息

Radiol Case Rep. 2024 Aug 5;19(10):4549-4553. doi: 10.1016/j.radcr.2024.07.074. eCollection 2024 Oct.

DOI:10.1016/j.radcr.2024.07.074
PMID:39206339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11357830/
Abstract

Giant cell arteritis is a form of large vessel vasculitis which can present with nonspecific symptoms, and if left untreated can cause significant morbidity and/or death. Early diagnosis and management are therefore paramount. The use of [F]FDG PET/CT in the evaluation of giant cell arteritis has increased in recent years, with newer generation PET scanners capturing the historically elusive cranial vessel inflammation in active vasculitis. We present a case of giant cell arteritis which was suspected on conventional imaging modalities, and subsequently evaluated with [F]FDG PET/CT which revealed marked vascular inflammation involving both cranial and other large vessels.

摘要

巨细胞动脉炎是一种大血管血管炎,可表现为非特异性症状,若不治疗可导致严重的发病和/或死亡。因此,早期诊断和治疗至关重要。近年来,[F]FDG PET/CT在巨细胞动脉炎评估中的应用有所增加,新一代PET扫描仪能够捕捉到既往难以发现的活动性血管炎中的颅血管炎症。我们报告一例巨细胞动脉炎病例,该病例在传统成像方式下被怀疑,随后通过[F]FDG PET/CT进行评估,结果显示颅血管和其他大血管均有明显的血管炎症。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/d9b69919524d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/9e557a5a29d3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/7c171e5b0f39/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/d9b69919524d/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/9e557a5a29d3/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/7c171e5b0f39/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a9c/11357830/d9b69919524d/gr3.jpg

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本文引用的文献

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Role of F-FDG PET/CT in Large Vessel Vasculitis and Polymyalgia Rheumatica.F-FDG PET/CT在大血管血管炎和风湿性多肌痛中的作用。
J Nucl Med. 2023 Apr;64(4):515-521. doi: 10.2967/jnumed.122.265016.
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Giant cell arteritis: A case report and review of literature.巨细胞动脉炎:一例病例报告及文献综述
Radiol Case Rep. 2021 Oct 2;16(12):3734-3738. doi: 10.1016/j.radcr.2021.08.072. eCollection 2021 Dec.
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Visual and semiquantitative assessment of cranial artery inflammation with FDG-PET/CT in giant cell arteritis.巨细胞动脉炎患者应用 FDG-PET/CT 进行颅动脉炎症的视觉和半定量评估。
Semin Arthritis Rheum. 2020 Aug;50(4):616-623. doi: 10.1016/j.semarthrit.2020.04.002. Epub 2020 Jun 2.
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Diagnostic performance of F-FDG PET-CT for large vessel involvement assessment in patients with suspected giant cell arteritis and negative temporal artery biopsy.18F-FDG PET-CT 对疑诊巨细胞动脉炎且颞动脉活检阴性患者大血管受累评估的诊断性能。
Ann Nucl Med. 2019 Jul;33(7):512-520. doi: 10.1007/s12149-019-01358-5. Epub 2019 Apr 11.
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Simple dichotomous assessment of cranial artery inflammation by conventional 18F-FDG PET/CT shows high accuracy for the diagnosis of giant cell arteritis: a case-control study.常规 18F-FDG PET/CT 对颅动脉炎症的简单二分法评估对巨细胞动脉炎的诊断具有很高的准确性:一项病例对照研究。
Eur J Nucl Med Mol Imaging. 2019 Jan;46(1):184-193. doi: 10.1007/s00259-018-4106-0. Epub 2018 Jul 31.
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Use of Noninvasive Imaging in Giant Cell Arteritis.巨细胞动脉炎的无创影像学应用。
Asia Pac J Ophthalmol (Phila). 2018 Jul-Aug;7(4):260-264. doi: 10.22608/APO.2018133. Epub 2018 Jul 13.
7
Three days of high-dose glucocorticoid treatment attenuates large-vessel 18F-FDG uptake in large-vessel giant cell arteritis but with a limited impact on diagnostic accuracy.大剂量糖皮质激素治疗 3 天可减轻大动脉型巨细胞动脉炎患者 18F-FDG 摄取,但对诊断准确性的影响有限。
Eur J Nucl Med Mol Imaging. 2018 Jul;45(7):1119-1128. doi: 10.1007/s00259-018-4021-4. Epub 2018 Apr 18.
8
FDG-PET/CT(A) imaging in large vessel vasculitis and polymyalgia rheumatica: joint procedural recommendation of the EANM, SNMMI, and the PET Interest Group (PIG), and endorsed by the ASNC.FDG-PET/CT(A)成像在大血管血管炎和巨细胞动脉炎中的应用:EANM、SNMMI 和 PET 兴趣小组(PIG)的联合程序建议,并得到 ASNC 的认可。
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