Main S J, Davies R V, Setchell B P
J Reprod Fertil Suppl. 1979(26):3-14.
The historical development of the 'inhibin' hypothesis is restated and the recent evidence reviewed. The circumstantial evidence for inhibin now seems very strong, and it probably acts in both sexes. Active materials have been isolated from several sources but it is not clear which is the circulating form of inhibin and a reciprocal relationship between circulating inhibin and FSH levels has not yet been demonstrated. Nevertheless, it appears that we may be optimistic about the existence of inhibin though the importance of its role as a physiological feedback inhibitor is still controversial.
“抑制素”假说的历史发展被重新阐述，并对近期证据进行了回顾。目前，支持抑制素存在的间接证据似乎非常有力，而且它可能在两性中都发挥作用。已经从多个来源分离出了活性物质，但尚不清楚哪种是抑制素的循环形式，并且循环抑制素与促卵泡激素水平之间的相互关系尚未得到证实。然而，尽管其作为生理反馈抑制剂的作用的重要性仍存在争议，但我们似乎有理由对抑制素的存在持乐观态度。
