• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

仅使用局部麻醉进行阴茎和阴囊泌尿外科手术:一项关于无镇静方案患者耐受性和手术结果的前瞻性研究。

Utilizing Local Anesthesia Only for Penile and Scrotal Urologic Surgery: A Prospective Study on Patient Tolerability and Surgical Outcomes for a Sedation-free Option.

作者信息

Bal Dhiraj S, Chung David, Urichuk Matthew, Shah Jainik, Fidel Maximilian G, Panchendrabose Kapilan, Sidhom Karim, Bard Robert, Nayak Jasmir G, Patel Premal

机构信息

Max Rady College of Medicine, University of Manitoba, Winnipeg, MB.

Section of Urology, Department of Surgery, University of Manitoba, Winnipeg, MB.

出版信息

Urology. 2024 Dec;194:7-13. doi: 10.1016/j.urology.2024.08.051. Epub 2024 Aug 28.

DOI:10.1016/j.urology.2024.08.051
PMID:39208947
Abstract

OBJECTIVE

To prospectively assess surgical outcomes, complications, and patient-reported tolerability of invasive scrotal surgeries under local anesthesia (LA) alone, without sedation, compared to tolerability of penile procedures commonly performed in this manner.

METHODS

Adult patients undergoing penile and scrotal surgeries under LA only were enrolled from August 2022 to June 2023 (NCT05617261). Demographics, surgeon-perceived and patient-reported pain, and surgical variables were collected. Tolerability to the procedures and future anesthetic choice for a repeat procedure was assessed on follow-up. Complication data were collected, including recurrence, infection, excessive pain, and emergency room and family physician visits.

RESULTS

Hundred and seven patients were enrolled with a mean age ± SD of 42.2 ± 16.4 years. There was a 100% procedural success rate and no cases of perioperative complications or escalation of anesthetic. Around 92.4% (n = 97) of patients indicated they would opt for LA only for a hypothetical repeat procedure. Of the minority opting for general anesthetic, most indicated discomfort or preferring an element of amnesia. No differences between intraoperative pain or tolerability scores of invasive scrotal procedures compared to penile procedures were observed. On univariate analysis, longer procedure duration (P = .003), cannabis use (P = .01), and higher intra-operative pain (P = .005) was associated with lower tolerability.

CONCLUSION

LA alone in an office-based setting is promising for scrotal surgeries. It offers similarly high patient tolerability compared to procedures that are routinely performed under LA, with the preservation of outcomes. Adopting this method has the potential for substantial cost savings, reduced wait times, enhanced accessibility, and improved surgical efficiency.

摘要

目的

前瞻性评估单纯局部麻醉(LA)且无镇静情况下进行侵入性阴囊手术的手术效果、并发症及患者报告的耐受性,并与通常以这种方式进行的阴茎手术的耐受性进行比较。

方法

2022年8月至2023年6月招募仅接受局部麻醉下阴茎和阴囊手术的成年患者(NCT05617261)。收集人口统计学数据、外科医生感知和患者报告的疼痛以及手术变量。随访时评估对手术的耐受性以及重复手术时未来的麻醉选择。收集并发症数据,包括复发、感染、过度疼痛以及急诊室就诊和家庭医生就诊情况。

结果

共招募了107例患者,平均年龄±标准差为42.2±16.4岁。手术成功率为100%,无围手术期并发症或麻醉升级病例。约92.4%(n = 97)的患者表示,对于假设的重复手术,他们会选择仅接受局部麻醉。在选择全身麻醉的少数患者中,大多数表示有不适感或希望有遗忘效果。与阴茎手术相比,未观察到侵入性阴囊手术的术中疼痛或耐受性评分有差异。单因素分析显示,手术时间较长(P = 0.003)、使用大麻(P = 0.01)和术中疼痛较高(P = 0.005)与耐受性较低相关。

结论

在门诊环境中单纯使用局部麻醉进行阴囊手术很有前景。与常规在局部麻醉下进行的手术相比,它具有同样高的患者耐受性,且能保持手术效果。采用这种方法有可能大幅节省成本、减少等待时间、提高可及性并改善手术效率。

相似文献

1
Utilizing Local Anesthesia Only for Penile and Scrotal Urologic Surgery: A Prospective Study on Patient Tolerability and Surgical Outcomes for a Sedation-free Option.仅使用局部麻醉进行阴茎和阴囊泌尿外科手术:一项关于无镇静方案患者耐受性和手术结果的前瞻性研究。
Urology. 2024 Dec;194:7-13. doi: 10.1016/j.urology.2024.08.051. Epub 2024 Aug 28.
2
Single-Stage Pedicle Preputial Tube Substitution Urethroplasty with Corpora Cavernosa Augmentation Using Buccal Mucosa Graft for Primary Peno-Scrotal Hypospadias Re-pair in Adults.单阶段带蒂包皮管替代尿道成形术联合阴茎海绵体增大术,采用颊黏膜移植治疗成人原发性阴茎阴囊型尿道下裂修复术
Int Braz J Urol. 2025 Jul-Aug;51(4). doi: 10.1590/S1677-5538.IBJU.2024.0650.
3
Comparison of Two Modern Survival Prediction Tools, SORG-MLA and METSSS, in Patients With Symptomatic Long-bone Metastases Who Underwent Local Treatment With Surgery Followed by Radiotherapy and With Radiotherapy Alone.两种现代生存预测工具 SORG-MLA 和 METSSS 在接受手术联合放疗和单纯放疗治疗有症状长骨转移患者中的比较。
Clin Orthop Relat Res. 2024 Dec 1;482(12):2193-2208. doi: 10.1097/CORR.0000000000003185. Epub 2024 Jul 23.
4
What Are the Recurrence Rates, Complications, and Functional Outcomes After Multiportal Arthroscopic Synovectomy for Patients With Knee Diffuse-type Tenosynovial Giant-cell Tumors?膝关节弥漫型腱鞘巨细胞瘤患者行多入路关节镜下滑膜切除术的复发率、并发症及功能结局如何?
Clin Orthop Relat Res. 2024 Jul 1;482(7):1218-1229. doi: 10.1097/CORR.0000000000002934. Epub 2023 Dec 28.
5
What is the value of routinely testing full blood count, electrolytes and urea, and pulmonary function tests before elective surgery in patients with no apparent clinical indication and in subgroups of patients with common comorbidities: a systematic review of the clinical and cost-effective literature.在没有明显临床指征的患者和常见合并症患者亚组中,在择期手术前常规检测全血细胞计数、电解质和尿素以及肺功能测试的价值:对临床和成本效益文献的系统评价。
Health Technol Assess. 2012 Dec;16(50):i-xvi, 1-159. doi: 10.3310/hta16500.
6
Does Minimally Invasive Surgery Provide Better Clinical or Radiographic Outcomes Than Open Surgery in the Treatment of Hallux Valgus Deformity? A Systematic Review and Meta-analysis.微创外科治疗拇外翻畸形是否优于开放手术:系统评价和荟萃分析。
Clin Orthop Relat Res. 2023 Jun 1;481(6):1143-1155. doi: 10.1097/CORR.0000000000002471. Epub 2022 Nov 4.
7
Does Augmenting Irradiated Autografts With Free Vascularized Fibula Graft in Patients With Bone Loss From a Malignant Tumor Achieve Union, Function, and Complication Rate Comparably to Patients Without Bone Loss and Augmentation When Reconstructing Intercalary Resections in the Lower Extremity?对于因恶性肿瘤导致骨缺损的患者,在重建下肢节段性切除时,采用带血管游离腓骨移植来增强照射后的自体骨移植,其骨愈合、功能及并发症发生率与无骨缺损且未进行增强的患者相比是否相当?
Clin Orthop Relat Res. 2025 Jun 26. doi: 10.1097/CORR.0000000000003599.
8
Use of hyaluronidase as an adjunct to local anaesthetic eye blocks to reduce intraoperative pain in adults.透明质酸酶作为局部麻醉性眼部阻滞辅助药物用于减轻成人术中疼痛。
Cochrane Database Syst Rev. 2018 Mar 2;3(3):CD010368. doi: 10.1002/14651858.CD010368.pub2.
9
What Are the Complications, Function, and Survival of Tumor-devitalized Autografts Used in Patients With Limb-sparing Surgery for Bone and Soft Tissue Tumors? A Japanese Musculoskeletal Oncology Group Multi-institutional Study.肿瘤灭活自体移植物用于保肢手术治疗骨和软组织肿瘤患者的并发症、功能和生存情况如何?日本肌肉骨骼肿瘤学组多机构研究。
Clin Orthop Relat Res. 2023 Nov 1;481(11):2110-2124. doi: 10.1097/CORR.0000000000002720. Epub 2023 Jun 14.
10
Intracavity lavage and wound irrigation for prevention of surgical site infection.腔内灌洗和伤口冲洗预防手术部位感染
Cochrane Database Syst Rev. 2017 Oct 30;10(10):CD012234. doi: 10.1002/14651858.CD012234.pub2.

引用本文的文献

1
Randomized controlled trial comparing the effects of methoxyflurane and local anesthesia combination to local anesthesia alone in scrotal surgery.比较甲氧氟烷与局部麻醉联合应用和单纯局部麻醉在阴囊手术中效果的随机对照试验。
Can Urol Assoc J. 2025 Aug;19(8):230-235. doi: 10.5489/cuaj.9311.
2
Comparative Analysis of Local Versus General Anesthesia and Its Impact on Erectile Dysfunction Risk Following Penile Surgery.阴茎手术中局部麻醉与全身麻醉的对比分析及其对勃起功能障碍风险的影响
Cureus. 2025 Jun 13;17(6):e85931. doi: 10.7759/cureus.85931. eCollection 2025 Jun.
3
Subtotal Scrotectomy and Scrotoplasty: An Effective Treatment for Idiopathic Scrotal Calcinosis.
阴囊次全切除术和阴囊成形术:治疗特发性阴囊钙化的有效方法。
Acta Derm Venereol. 2025 May 13;105:adv43100. doi: 10.2340/actadv.v105.43100.