Revisiting diagnostics: erythrocyte sedimentation rate and C-reactive protein: it is time to stop the zombie tests.
作者信息
Spellberg Brad, Nielsen Travis B, Phillips Matthew C, Ghanem Bassam, Boyles Tom, Jegorović Boris, Footer Brent, Mah Jordan K, Lieu Anthony, Scott Jake, Wald-Dickler Noah, Lee Todd C, McDonald Emily G
机构信息
Hospital Administration, Los Angeles General Medical Center, Los Angeles, CA, USA.
Division of Infectious Diseases & Global Public Health, Department of Medicine, University of California San Diego, La Jolla, CA, USA; Department of Molecular Microbiology and Immunology, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA.
出版信息
Clin Microbiol Infect. 2025 Jan;31(1):1-4. doi: 10.1016/j.cmi.2024.08.017. Epub 2024 Aug 28.
Abstract
摘要
相似文献
1
Revisiting diagnostics: erythrocyte sedimentation rate and C-reactive protein: it is time to stop the zombie tests.重新审视诊断指标：红细胞沉降率和C反应蛋白：是时候停止这些无用的检测了。
Clin Microbiol Infect. 2025 Jan;31(1):1-4. doi: 10.1016/j.cmi.2024.08.017. Epub 2024 Aug 28.
2
Procalcitonin, C-reactive protein, and erythrocyte sedimentation rate for the diagnosis of acute pyelonephritis in children.降钙素原、C反应蛋白及红细胞沉降率用于儿童急性肾盂肾炎的诊断
Cochrane Database Syst Rev. 2015 Jan 20;1(1):CD009185. doi: 10.1002/14651858.CD009185.pub2.
3
Screening for Infection Before Revision Hip Arthroplasty: A Meta-analysis of Likelihood Ratios of Erythrocyte Sedimentation Rate and Serum C-reactive Protein Levels.翻修髋关节置换术前感染筛查：红细胞沉降率和血清 C 反应蛋白水平似然比的荟萃分析。
J Am Acad Orthop Surg. 2017 Dec;25(12):809-817. doi: 10.5435/JAAOS-D-16-00642.
4
Comparison of Neutrophil-Lympocyte Ratio, Platelet-Lymphocyte Ratio with C-Reactive Protein and Erythrocyte Sedimentation Rate in Mandibular Odontogenic Space Infection Cases: A Clinical Study.下颌牙源性间隙感染病例中中性粒细胞与淋巴细胞比值、血小板与淋巴细胞比值与C反应蛋白和红细胞沉降率的比较：一项临床研究
J Maxillofac Oral Surg. 2025 Apr;24(2):489-499. doi: 10.1007/s12663-024-02220-6. Epub 2024 Jun 18.
5
Admission Neutrophil-to-Lymphocyte Ratio Is Superior to WBC Count at Predicting the Presence and Severity of Pediatric Musculoskeletal Infection.入院时中性粒细胞与淋巴细胞比值在预测小儿肌肉骨骼感染的存在及严重程度方面优于白细胞计数。
J Bone Joint Surg Am. 2025 Apr 16;107(8):868-877. doi: 10.2106/JBJS.24.00481. Epub 2025 Feb 25.
6
No added value of the neutrophil-lymphocyte ratio (NLR) and platelet count to mean platelet volume ratio (PC/MPV) over the traditional serum markers (ESR and CRP) in the diagnosis of periprosthetic joint infection (PJI).在人工关节周围感染（PJI）的诊断中，中性粒细胞与淋巴细胞比值（NLR）和血小板计数与平均血小板体积比值（PC/MPV）相较于传统血清标志物（红细胞沉降率和C反应蛋白）并无额外的诊断价值。
Knee Surg Sports Traumatol Arthrosc. 2025 Jul 13. doi: 10.1002/ksa.12768.
7
Results of Aspiration, Erythrocyte Sedimentation Rate, and C-Reactive Protein in Patients With Known Prosthetic Joint Infection on Chronic Suppression.慢性抑制治疗下已知人工关节感染患者的抽吸、红细胞沉降率及C反应蛋白结果
J Am Acad Orthop Surg Glob Res Rev. 2025 Jun 11;9(6). doi: 10.5435/JAAOSGlobal-D-25-00139. eCollection 2025 Jun 1.
8
An Assessment of C-Reactive Protein and Erythrocyte Sedimentation Rate in Ruling Out Acute Infectious Spinal Pathology in Emergency Department Patients: A Retrospective Cohort Study.评估C反应蛋白和红细胞沉降率在排除急诊科患者急性感染性脊柱病变中的作用：一项回顾性队列研究。
J Am Coll Emerg Physicians Open. 2025 Jul 11;6(4):100213. doi: 10.1016/j.acepjo.2025.100213. eCollection 2025 Aug.
9
Normal inflammatory markers in giant cell arteritis: a diagnostic blind spot.巨细胞动脉炎中正常的炎症标志物：一个诊断盲点。
Rheumatol Int. 2025 Jul 19;45(8):175. doi: 10.1007/s00296-025-05930-3.
10
A meta-analysis of the utility of C-reactive protein, erythrocyte sedimentation rate, fecal calprotectin, and fecal lactoferrin to exclude inflammatory bowel disease in adults with IBS.一项关于 C 反应蛋白、红细胞沉降率、粪便钙卫蛋白和乳铁蛋白在排除 IBS 成人炎症性肠病中的效用的荟萃分析。
Am J Gastroenterol. 2015 Mar;110(3):444-54. doi: 10.1038/ajg.2015.6. Epub 2015 Mar 3.
引用本文的文献
1
Interplay between C-reactive protein responses and antibiotic prescribing in people with suspected infection.疑似感染患者中C反应蛋白反应与抗生素处方之间的相互作用。
BMC Infect Dis. 2025 Aug 5;25(1):987. doi: 10.1186/s12879-025-11381-9.
2
Association of Daily Body Temperature, White Blood Cell Count, and C-reactive Protein With Mortality and Persistent Bacteremia in Patients With Bacteremia: A Post Hoc Analysis of the CAMERA2 Randomized Clinical Trial.菌血症患者的每日体温、白细胞计数及C反应蛋白与死亡率和持续性菌血症的关联：CAMERA2随机临床试验的事后分析
Open Forum Infect Dis. 2025 Jan 30;12(2):ofaf063. doi: 10.1093/ofid/ofaf063. eCollection 2025 Feb.
本文引用的文献
1
Impact of C-reactive protein point-of-care testing on antibiotic prescriptions for children and adults with suspected respiratory tract infections in primary care: a French patient-level randomized controlled superiority trial.C 反应蛋白即时检测对初级保健中疑似呼吸道感染的儿童和成人抗生素处方的影响：一项法国患者水平随机对照优效性试验。
Clin Microbiol Infect. 2024 Dec;30(12):1553-1558. doi: 10.1016/j.cmi.2024.07.014. Epub 2024 Jul 26.
2
Reducing Erythrocyte Sedimentation Rate Ordering: De-implementation and Diagnostic Stewardship.红细胞沉降率检测医嘱精简：去执行化和诊断管理
Hosp Pediatr. 2024 Aug 1;14(8):658-665. doi: 10.1542/hpeds.2023-007642.
3
Update of biomarkers to diagnose diabetic foot osteomyelitis: A meta-analysis and systematic review.诊断糖尿病足骨髓炎的生物标志物更新：荟萃分析和系统评价。
Wound Repair Regen. 2024 Jul-Aug;32(4):366-376. doi: 10.1111/wrr.13174. Epub 2024 Apr 2.
4
Diagnostic test accuracy of procalcitonin and C-reactive protein for predicting invasive and serious bacterial infections in young febrile infants: a systematic review and meta-analysis.降钙素原和 C 反应蛋白预测发热婴幼儿侵袭性和严重细菌感染的诊断准确性：系统评价和荟萃分析。
Lancet Child Adolesc Health. 2024 May;8(5):358-368. doi: 10.1016/S2352-4642(24)00021-X. Epub 2024 Mar 16.
5
Erythrocyte Sedimentation Rate for Assisted Diagnosis of Pediatric Osteomyelitis: A Meta-Analysis.红细胞沉降率用于小儿骨髓炎辅助诊断的Meta分析
Ther Clin Risk Manag. 2023 Dec 7;19:1039-1049. doi: 10.2147/TCRM.S440996. eCollection 2023.
6
Utility of Diagnostic Tests Before Reimplantation in Patients Undergoing 2-Stage Revision Total Joint Arthroplasty: A Systematic Review and Meta-analysis.2 期翻修全关节置换术患者再植入前诊断试验的效用：系统评价和荟萃分析。
JBJS Rev. 2023 Mar 22;11(3). doi: e22.00201. eCollection 2023 Mar 1.
7
Principles of diagnostic stewardship: A practical guide from the Society for Healthcare Epidemiology of America Diagnostic Stewardship Task Force.诊断管理原则：美国医疗保健流行病学学会诊断管理工作组实用指南。
Infect Control Hosp Epidemiol. 2023 Feb;44(2):178-185. doi: 10.1017/ice.2023.5.
8
Reliable Diagnostic Tests and Thresholds for Preoperative Diagnosis of Non-Inflammatory Arthritis Periprosthetic Joint Infection: A Meta-analysis and Systematic Review.可靠的诊断检测方法和术前非炎性关节炎人工关节置换术后感染阈值：荟萃分析和系统评价。
Orthop Surg. 2022 Nov;14(11):2822-2836. doi: 10.1111/os.13500. Epub 2022 Oct 1.
9
Use of biomarkers to individualize antimicrobial therapy duration: a narrative review.使用生物标志物个体化抗菌治疗疗程：一项叙述性综述
Clin Microbiol Infect. 2023 Feb;29(2):160-164. doi: 10.1016/j.cmi.2022.08.026. Epub 2022 Sep 10.
10
Use of Novel Strategies to Develop Guidelines for Management of Pyogenic Osteomyelitis in Adults: A WikiGuidelines Group Consensus Statement.采用新策略制定成人化脓性骨髓炎管理指南：WikiGuidelines 小组共识声明。
JAMA Netw Open. 2022 May 2;5(5):e2211321. doi: 10.1001/jamanetworkopen.2022.11321.
Zotero 插件