College of Pharmacy, Yeungnam University, Gyeongsan, Korea (the Republic of)
Department of Health Sciences, University of York, York, UK.
BMJ Open Respir Res. 2024 Aug 28;11(1):e002472. doi: 10.1136/bmjresp-2024-002472.
The existing evidence for the impacts of continuity of care (COC) in patients with chronic obstructive pulmonary disease (COPD) is low to moderate. This study aimed to investigate the associations between relational COC within primary care and COPD-related hospitalisations using a robust methodology.
Population-based cohort study.
National Health Insurance Service database, South Korea.
92 977 adults (≥40 years) with COPD newly diagnosed between 2015 and 2016 were included. The propensity score (PS) matching approach was used. PSs were calculated from a multivariable logistic regression that included eight baseline characteristics.
COC within primary care.
The primary outcome was the incidence of COPD-related hospitalisations. Cox proportional hazard models were used to estimate HRs and 95% CIs.
Out of 92 977 patients, 66 677 of whom were cared for continuously by primary doctors (the continuity group), while 26 300 were not (the non-continuity group). During a 4-year follow-up period, 2094 patients (2.25%) were hospitalised; 874 (1.31%) from the continuity group and 1220 (4.64%) from the non-continuity group. After adjusting for confounding covariates, patients in the non-continuity group exhibited a significantly higher risk of hospital admission (adjusted HR (aHR) 2.43 (95% CI 2.22 to 2.66)). This risk was marginally reduced to 2.21 (95% CI 1.99 to 2.46) after PS matching. The risk of emergency department (ED) visits, systemic corticosteroid use and costs were higher for patients in the non-continuity group (aHR 2.32 (95% CI 2.04 to 2.63), adjusted OR 1.25 (95% CI 1.19 to 1.31) and exp=1.89 (95% CI 1.82 to 1.97), respectively). These findings remained consistent across the PS-matched cohort, as well as in the sensitivity and subgroup analyses.
In patients with COPD aged over 40, increased continuity of primary care was found to be associated with less hospitalisation, fewer ED visits and lower healthcare expenditure.
现有证据表明,连续性护理(COC)对慢性阻塞性肺疾病(COPD)患者的影响程度为低到中度。本研究旨在采用稳健的方法探讨初级保健中COC 与 COPD 相关住院之间的关联。
基于人群的队列研究。
韩国国家健康保险服务数据库。
纳入 2015 年至 2016 年期间新诊断为 COPD 的 92977 名成年人(≥40 岁)。采用倾向评分(PS)匹配方法。PS 是从包含 8 个基线特征的多变量逻辑回归中计算得出的。
初级保健中的 COC。
主要结局是 COPD 相关住院的发生率。使用 Cox 比例风险模型估计 HRs 和 95%置信区间。
在 92977 名患者中,有 66677 名患者由初级医生持续照顾(连续性组),而 26300 名患者未由初级医生持续照顾(非连续性组)。在 4 年的随访期间,有 2094 名患者(2.25%)住院;连续性组 874 名(1.31%),非连续性组 1220 名(4.64%)。调整混杂协变量后,非连续性组患者的住院风险显著增加(调整后的 HR[aHR]2.43[95%CI 2.22 至 2.66])。在进行 PS 匹配后,这一风险略微降低至 2.21(95%CI 1.99 至 2.46)。非连续性组患者的急诊就诊、全身皮质类固醇使用和成本风险更高(aHR 2.32[95%CI 2.04 至 2.63],调整后的 OR 1.25[95%CI 1.19 至 1.31]和 exp=1.89[95%CI 1.82 至 1.97])。这些发现与 PS 匹配队列以及敏感性和亚组分析一致。
在年龄超过 40 岁的 COPD 患者中,初级保健的连续性增加与住院次数减少、急诊就诊次数减少和医疗保健支出降低有关。