Department of Orthopaedic Surgery, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan.
Department of Orthopaedic Surgery, Chutoen General Medical Center, 1-1 Shobugaike, Kakegaswa-Shi, Shizuoka-Ken, 436-8555, Japan.
Eur J Orthop Surg Traumatol. 2024 Dec;34(8):3947-3953. doi: 10.1007/s00590-024-04083-6. Epub 2024 Aug 30.
Heterotopic ossification (HO) can occur after hemiarthroplasty (HA) for femoral neck fractures (FNF). This study aimed to investigate the frequency and factors contributing to the development of HO after HA.
The study included data from 92 of 183 patients (26 male and 66 female) who sustained FNF and underwent HA between April 2019 and January 2022. HO was identified on postoperative radiographic images. Patient background, operative duration, blood loss, and presence of free bone fragments immediately after surgery were compared between the HO and non-HO groups. Statistical analyses included the independent-sample t-test for continuous variables and the chi-squared test for categorical variables. A multivariate logistic regression analysis was performed using HO as an objective variable.
HO occurred in 50 of the 92 (54%) patients. There were no statistically significant differences in patient backgrounds. Univariate analysis revealed significantly longer mean operative duration and greater blood loss in the HO group. Free bone fragments in the immediate postoperative period were observed in 29 of 50 (58%) patients in the HO group and in 3 of 42 (7.1%) patients in the non-HO group, a statistically significant difference. Logistic regression analysis revealed that the presence of free bone fragments was an independent explanatory factor for HO development.
The presence of free bone fragments immediately after surgery may be significantly associated with the development of HO. Therefore, it is necessary to sufficiently remove such fragments during surgery because they may trigger HO.
髋关节置换术(HA)后可发生异位骨化(HO)。本研究旨在探讨 HA 后 HO 发生的频率及相关因素。
研究纳入了 2019 年 4 月至 2022 年 1 月期间因股骨颈骨折(FNF)接受 HA 的 183 例患者中的 92 例(26 名男性,66 名女性)。术后影像学上发现 HO。比较 HO 组和非 HO 组患者的背景、手术时间、失血量以及术后即刻游离骨碎片的存在情况。连续变量采用独立样本 t 检验,分类变量采用卡方检验。HO 作为因变量进行多因素 logistic 回归分析。
92 例患者中有 50 例(54%)发生 HO。两组患者的背景无统计学差异。单因素分析显示 HO 组的平均手术时间和失血量显著较长。HO 组 50 例(58%)患者和非 HO 组 42 例(7.1%)患者在术后即刻均有游离骨碎片,差异有统计学意义。多因素 logistic 回归分析显示,术后即刻存在游离骨碎片是 HO 发生的独立解释因素。
术后即刻存在游离骨碎片可能与 HO 的发生显著相关。因此,术中需要充分清除这些游离骨碎片,因为它们可能引发 HO。