兔脂肪酸合酶硫酯酶结构域反应性丝氨酸残基周围的氨基酸序列。
Amino acid sequence around the reactive serine residue of the thioesterase domain of rabbit fatty acid synthase.
作者信息
Hardie D G, Dewart K B, Aitken A, McCarthy A D
出版信息
Biochim Biophys Acta. 1985 Apr 29;828(3):380-2. doi: 10.1016/0167-4838(85)90320-6.
PMID:3921056
Abstract
Two thermolytic peptides containing the reactive serine residue of the thioesterase domain of rabbit fatty acid synthase have been isolated and sequenched by Edman degradation and fast atom bombardment mass spectrometry. The sequence (V-A-G-Y-S-Y-G) contains the motif G-X-S-X-G found around the reactive serine residue of all known serine proteinases and esterases.
摘要
已从兔脂肪酸合酶硫酯酶结构域中分离出两条含有活性丝氨酸残基的热解肽，并通过埃德曼降解法和快速原子轰击质谱法对其进行了测序。序列（V-A-G-Y-S-Y-G）包含在所有已知丝氨酸蛋白酶和酯酶的活性丝氨酸残基周围发现的基序G-X-S-X-G。
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