Zhang Wenjie, Zhao Jie, Zou Xinxin, Yu Jingrong, Liao Jinlong, Huang Fengjie
Department of Pharmaceutical Microbiology, School of Life Science and Technology, China Pharmaceutical University, Nanjing, China.
J Biomed Mater Res A. 2025 Jan;113(1):e37776. doi: 10.1002/jbm.a.37776. Epub 2024 Aug 29.
Oral ulcers are one of the most common oral diseases in clinical practice. Its etiology is complex and varied. Due to the dynamic nature of the oral environment, the wound surface is painful due to contact and wear, which seriously affects the quality of life of patients. Oral ulcers are often treated with topical drug therapy. Studies have shown that functional hydrogels play a positive role in promoting wound healing, showing unique advantages in wound dressings. In this paper, the causes and healing characteristics of oral ulcers are discussed in depth, and then the common treatment methods for oral ulcers are summarized and compared. Finally, the potential of functional hydrogels in the treatment of oral ulcers is discussed and projected through a review of the literature in recent years.
口腔溃疡是临床实践中最常见的口腔疾病之一。其病因复杂多样。由于口腔环境的动态特性，创面因接触和磨损而疼痛，严重影响患者的生活质量。口腔溃疡常采用局部药物治疗。研究表明，功能性水凝胶在促进伤口愈合方面发挥着积极作用，在伤口敷料方面显示出独特优势。本文深入探讨了口腔溃疡的成因和愈合特点，然后总结并比较了口腔溃疡的常见治疗方法。最后，通过对近年来文献的综述，探讨并预测了功能性水凝胶在口腔溃疡治疗中的潜力。
