早期定量脑电图对儿童重型颅脑损伤后癫痫的预测价值
The predicative value of early quantitative electroencephalograph in epilepsy after severe traumatic brain injury in children.
作者信息
Bai Wei
机构信息
Department of Pediatrics, Xiangyang NO.1 People's Hospital, Xiangyang, Hubei, China.
出版信息
Front Pediatr. 2024 Aug 15;12:1370692. doi: 10.3389/fped.2024.1370692. eCollection 2024.
OBJECTIVE
To explore whether early quantitative electroencephalograph (EEG) can predict the development of epilepsy in pediatric patients with severe traumatic brain injury (TBI).
METHODS
A total of 78 children with severe TBI who were admitted to our hospital were divided into post-traumatic epilepsy (PTE) and non-PTE groups according to whether or not they developed PTE. EEGs of frontal, central and parietal lobes were recorded at the time of their admission. The power values of each frequency band, odds ratio and peak envelope power values of each brain region were statistically analyzed. In addition, the patients were followed up for two years, and the occurrence of PTE was documented.
RESULTS
During the follow-up period, PTE occurred in 8 patients. Analysis of EEG signals across different brain regions (frontal, central, and parietal lobes) revealed significant differences between the PTE and non-PTE groups. Patients with PTE exhibited significantly higher δ and θ power values ( < 0.01), lower α/θ ratios ( < 0.01), and elevated θ/β, (δ + θ)/(α + β), and peak envelope power ( < 0.01) compared to those in the non-PTE group.
CONCLUSION
In children with severe TBI, the parameter characterization of early quantitative EEG has potential application in predicting PTE.
目的
探讨早期定量脑电图（EEG）能否预测小儿重型颅脑损伤（TBI）患者癫痫的发生。
方法
选取我院收治的78例重型TBI患儿，根据是否发生创伤后癫痫（PTE）分为PTE组和非PTE组。入院时记录额叶、中央叶和顶叶的脑电图。对各频段的功率值、优势比和各脑区的峰值包络功率值进行统计学分析。此外，对患者进行了两年的随访，并记录PTE的发生情况。
结果
随访期间，8例患者发生PTE。对不同脑区（额叶、中央叶和顶叶）的脑电信号分析显示，PTE组和非PTE组之间存在显著差异。与非PTE组相比，PTE患者的δ和θ功率值显著更高（<0.01），α/θ比值更低（<0.01），θ/β、（δ+θ）/（α+β）和峰值包络功率升高（<0.01）。
结论
在小儿重型TBI患者中，早期定量脑电图的参数特征在预测PTE方面具有潜在应用价值。
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