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伴有淋巴囊肿的子宫内膜癌的自适应放射治疗:一例报告

Adaptive Radiotherapy for Carcinoma Endometrium With Lymphocele: A Case Report.

作者信息

Weerarathna Induni N, Uke Ashish, Jules Manishimwe, Dahake Shweta B, Luharia Anurag

机构信息

Biomedical Sciences, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

Radiation Oncology, Datta Meghe Institute of Higher Education and Research, Wardha, IND.

出版信息

Cureus. 2024 Jul 30;16(7):e65775. doi: 10.7759/cureus.65775. eCollection 2024 Jul.

DOI:10.7759/cureus.65775
PMID:39211668
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11361454/
Abstract

The case report details the adaptive radiotherapy management of a 75-year-old female diagnosed with high-grade endometrial carcinoma. The patient, who was known to be hypertensive with no other comorbidities and no family history of cancer, presented with a complaint of bleeding per vagina for six months. Following extensive investigations, she underwent a laparoscopic radical hysterectomy. Postoperative histopathology confirmed endometrial adenocarcinoma International Federation of Gynecology and Obstetrics (FIGO) stage IA, grade III. The adjuvant treatment plan included adjuvant chemoradiotherapy to the postoperative tumor bed and draining lymph nodes. On planning computed tomography (CT), the patient's lymphocele responded remarkably to radiation therapy, an unusual outcome that underscores the potential efficacy of adaptive radiotherapy in complex cases.

摘要

该病例报告详细介绍了一名75岁女性高级别子宫内膜癌的自适应放射治疗管理情况。该患者已知患有高血压,无其他合并症,且无癌症家族史,因阴道出血六个月前来就诊。经过广泛检查后,她接受了腹腔镜根治性子宫切除术。术后组织病理学证实为国际妇产科联盟(FIGO)IA期、III级子宫内膜腺癌。辅助治疗方案包括对术后肿瘤床和引流淋巴结进行辅助放化疗。在计划计算机断层扫描(CT)时,患者的淋巴囊肿对放射治疗反应显著,这一不寻常的结果突出了自适应放射治疗在复杂病例中的潜在疗效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/b8dae8683d7a/cureus-0016-00000065775-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/1d0a63f353cc/cureus-0016-00000065775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/0dcbdfafe33c/cureus-0016-00000065775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/314a4de97089/cureus-0016-00000065775-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/2e3ddda065ee/cureus-0016-00000065775-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/b8dae8683d7a/cureus-0016-00000065775-i05.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/1d0a63f353cc/cureus-0016-00000065775-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/0dcbdfafe33c/cureus-0016-00000065775-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/314a4de97089/cureus-0016-00000065775-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/2e3ddda065ee/cureus-0016-00000065775-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fcf/11361454/b8dae8683d7a/cureus-0016-00000065775-i05.jpg

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本文引用的文献

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Evaluation of PTV margins with daily iterative online adaptive radiotherapy for postoperative treatment of endometrial and cervical cancer: a prospective single-arm phase 2 study.评估每日迭代在线自适应放疗在子宫内膜癌和宫颈癌术后治疗中的应用:一项前瞻性单臂 2 期研究。
Radiat Oncol. 2024 Jan 4;19(1):2. doi: 10.1186/s13014-023-02394-2.
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An Overview of Endometrial Cancer with Novel Therapeutic Strategies.子宫内膜癌的治疗新策略概述。
Curr Oncol. 2023 Aug 27;30(9):7904-7919. doi: 10.3390/curroncol30090574.
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The New Kid on the Block: Online Adaptive Radiotherapy in the Treatment of Gynecologic Cancers.
崭露头角:在线自适应放疗在妇科癌症治疗中的应用。
Curr Oncol. 2023 Jan 8;30(1):865-874. doi: 10.3390/curroncol30010066.
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Current Approaches to the Management of Patients with Endometrial Cancer.子宫内膜癌患者的当前管理方法
Cancers (Basel). 2022 Sep 16;14(18):4500. doi: 10.3390/cancers14184500.
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Adjuvant vaginal cuff brachytherapy in surgically treated endometrial carcinoma patients - in view of the recent evidence.手术治疗子宫内膜癌患者的辅助阴道残端近距离放疗——鉴于最新证据
J Contemp Brachytherapy. 2021 Apr;13(2):221-230. doi: 10.5114/jcb.2021.105291. Epub 2021 Apr 14.
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Adaptive Radiation Therapy (ART) Strategies and Technical Considerations: A State of the ART Review From NRG Oncology.自适应放射治疗(ART)策略与技术考量:来自NRG肿瘤学的ART综述现状
Int J Radiat Oncol Biol Phys. 2021 Mar 15;109(4):1054-1075. doi: 10.1016/j.ijrobp.2020.10.021. Epub 2020 Oct 24.
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Adaptive Radiotherapy: Moving Into the Future.自适应放疗:迈向未来
Semin Radiat Oncol. 2019 Jul;29(3):181-184. doi: 10.1016/j.semradonc.2019.02.011.
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Brachytherapy: A critical component of primary radiation therapy for cervical cancer: From the Society of Gynecologic Oncology (SGO) and the American Brachytherapy Society (ABS).近距离放射治疗:子宫颈癌原发性放射治疗的关键组成部分:来自妇科肿瘤学会(SGO)和美国近距离放射治疗学会(ABS)
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Global cancer statistics 2018: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.全球癌症统计数据 2018:GLOBOCAN 对全球 185 个国家/地区 36 种癌症的发病率和死亡率的估计。
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