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Hyperexcretion of free N-acetylneuraminic acid--a novel type of sialuria.

作者信息

Palo J, Rauvala H, Finne J, Haltia M, Palmgren K

出版信息

Clin Chim Acta. 1985 Feb 15;145(3):237-42. doi: 10.1016/0009-8981(85)90029-4.

DOI:10.1016/0009-8981(85)90029-4
PMID:3921284
Abstract

A 26-yr-old female with increased urinary excretion of free N-acetylneuraminic acid is described. Her early history was normal but she had difficulties at school and developed epilepsy at 14. She is mildly retarded, has slight changes in the spine, but no hepato- or splenomegaly. Cerebrospinal fluid leucocytes and IgG are elevated. Liver and skin biopsies disclosed no morphological abnormality. The daily excretion of free N-acetylneuraminic acid is ca. 0.5 g, intermediate to that found in other known types of sialuria. The clinical and morphological findings are also different suggesting a novel type of sialuria.

摘要

相似文献

1
Hyperexcretion of free N-acetylneuraminic acid--a novel type of sialuria.
Clin Chim Acta. 1985 Feb 15;145(3):237-42. doi: 10.1016/0009-8981(85)90029-4.
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