National Engineering Research Center of Engineering Plastics and Ecological Plastics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China; University of Chinese Academy of Sciences, Beijing 100049, China.
National Engineering Research Center of Engineering Plastics and Ecological Plastics, Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100190, China; Hainan Degradable Plastics Technology Innovation Center, Haikou 571137, China.
Sci Total Environ. 2024 Nov 15;951:175729. doi: 10.1016/j.scitotenv.2024.175729. Epub 2024 Aug 29.
The development of environmentally responsive biodegradable polymers is a promising solution for balancing the stability and degradability of biodegradable plastics. In this study, a commercial biodegradable polyester, poly(butylene adipate-co-butylene terephthalate) (PBAT), was used as the substrate and was synthetically modified with a small amount of anionic sodium 1-3-isophthalate-5-sulfonate (SIPA) to obtain the ionized random poly(butylene adipate-co-butylene terephthalate-co-butylene 5-sodiosulfoisophthalate) (PBATS). The introduction of the sodium sulfonate ionic group enhanced the mechanical and heat-resistant properties of the material, while significantly improving the hydrophilicity and water absorption of the copolyesters of PBATSs and endowing them with special pH-responsive degradation properties. Compared with PBAT, PBATS copolyesters could accelerate degradation in acidic or alkaline buffer solutions and natural seawater, while degradation was inhibited in neutral buffer solutions at pH 7.2. Degradation experiments in simulated gastric, intestinal, and body fluids revealed that the copolyester showed specific and rapid degradation in acidic gastric fluids. This environmentally-responsive degradable material greatly expands the special applications of biodegradable polyesters in the fields of environmental remediation and medical applications.
开发对环境响应的可生物降解聚合物是平衡可生物降解塑料的稳定性和可降解性的一种有前途的解决方案。在本研究中，以商业化的可生物降解聚酯聚（己二酸丁二醇酯-对苯二甲酸丁二醇酯）（PBAT）为基质，少量阴离子 5-磺酸钠间苯二甲酸（SIPA）对其进行化学改性，得到离子化的无规共聚物聚（己二酸丁二醇酯-对苯二甲酸丁二醇酯-丁二酸 5-磺酸钠）（PBATS）。磺酸钠离子基团的引入增强了材料的机械和耐热性能，同时显著提高了 PBATS 共聚酯的亲水性和吸水性，并赋予其特殊的 pH 响应降解性能。与 PBAT 相比，PBATS 共聚酯在酸性或碱性缓冲溶液和天然海水中可以加速降解，而在中性缓冲溶液（pH 7.2）中降解受到抑制。在模拟胃液、肠液和体液中的降解实验表明，该共聚酯在酸性胃液中表现出特异性和快速降解。这种对环境响应的可降解材料极大地扩展了可生物降解聚酯在环境修复和医学应用等领域的特殊应用。
