Joint Department of Biomedical Engineering, Marquette University and Medical College of Wisconsin, Milwaukee, WI, USA; Zablocki Veterans Affairs Medical Center, Milwaukee, WI, USA.
Zablocki Veterans Affairs Medical Center, Milwaukee, WI, USA; Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.
J Mech Behav Biomed Mater. 2024 Nov;159:106710. doi: 10.1016/j.jmbbm.2024.106710. Epub 2024 Aug 28.
Ballistic gelatin has been extensively used in ballistics research for decades, but calibration standards were established on limited datasets, and only few studies have attempted to recreate these experiments with biological tissues. Recent studies have demonstrated better biofidelity with 20% ordnance ballistic gelatin, but researchers have discredited the use of synthetic gelatin claiming different behavior than ordnance gelatin. To investigate the use of synthetic clear gelatin as an acceptable surrogate of biological tissue, depth of penetration was compared between low-velocity impacts of various projectiles into porcine tissue (n = 192), post-mortem human subjects (n = 29), and Clear Ballistics synthetic gelatin (n = 39). The predicted depth of penetration of the 0.177" steel BB (38.1 mm) was consistent with the manufacturer's calibration standard (31.75-44.45 mm) and within calibration bounds of recently proposed empirical equations. Compared to impacts in biological tissue, synthetic gelatin demonstrated the least variability in depth of penetration (R = 0.96). Using ANCOVA, velocity was a significant covariate (p < 0.001), and there were no significant differences in normalized depth of penetration over density between porcine tissue, post-mortem human subjects, and 20% synthetic gelatin (p = 0.22). Ultimately, this study confirmed the use of 20% synthetic gelatin as an acceptable tissue simulant using standard calibration methods for use in future ballistic studies.
弹道凝胶在弹道学研究中已经被广泛应用了几十年,但校准标准是基于有限的数据集建立的,只有少数研究试图用生物组织来重现这些实验。最近的研究表明,20%的军用弹道凝胶具有更好的生物仿真度,但研究人员否定了合成凝胶的使用,声称其行为与军用凝胶不同。为了研究合成透明凝胶作为生物组织的可接受替代品的用途,本研究比较了各种弹丸在猪组织(n=192)、死后人体(n=29)和 Clear Ballistics 合成凝胶(n=39)中低速冲击的穿透深度。0.177" 钢 BB(38.1 毫米)的预测穿透深度与制造商的校准标准(31.75-44.45 毫米)一致,并且在最近提出的经验公式的校准范围内。与在生物组织中的冲击相比,合成凝胶在穿透深度上表现出最小的可变性(R=0.96)。使用协方差分析,速度是一个显著的协变量(p<0.001),在猪组织、死后人体和 20%合成凝胶之间,密度对归一化穿透深度没有显著影响(p=0.22)。最终,本研究通过使用标准校准方法,证实了 20%合成凝胶作为可接受的组织模拟物在未来弹道学研究中的使用。