仓鼠颊囊血管引流系统的研究。

Studies on the vascular drainage system of the hamster buccal pouch.

作者信息

Giunta J L, Schwartz J L, Antoniadis D

出版信息

J Oral Pathol. 1985 Mar;14(3):263-7. doi: 10.1111/j.1600-0714.1985.tb00490.x.

DOI:10.1111/j.1600-0714.1985.tb00490.x

Abstract

Because some investigators feel that the hamster buccal pouch is an immune privileged site with no lymphatic drainage, this study was done to demonstrate and further elucidate a drainage system from the pouch to the cervical nodes. Eight hamsters were injected with india ink, submucosally in the right pouch. Dissections at one or 2 days revealed ink in macrophages in the right submandibular nodes at 2 days. Histologically, the ink was noted within macrophages which aggregated around blood vessels. No lymph vessels were noted in the pouch. Six hamsters were injected with fluorochrome-labelled latex microspheres. At 2 and at 4 days the microspheres were noted in both the pouches and the ipsilateral submandibular nodes. The results indicate there is a delayed lymphatic drainage from cheek pouches to the submandibular nodes mediated by macrophages.

摘要

由于一些研究者认为仓鼠颊囊是一个没有淋巴引流的免疫特权部位，因此开展了本研究以证明并进一步阐明从颊囊到颈淋巴结的引流系统。给8只仓鼠右侧颊囊黏膜下注射印度墨水。在1天或2天后进行解剖，发现2天时右侧下颌下淋巴结的巨噬细胞中有墨水。组织学检查发现，墨水存在于围绕血管聚集的巨噬细胞内。在颊囊中未发现淋巴管。给6只仓鼠注射了荧光素标记的乳胶微球。在2天和4天时，在颊囊和同侧下颌下淋巴结中均发现了微球。结果表明，存在由巨噬细胞介导的从颊囊到下颌下淋巴结的延迟淋巴引流。