He Jiang, Zhang Wenli, Lv Jiabao, Yang Yaohong, Yuan Xushuo, Yao Jinzhong, Liu Li, Xu Kaimeng, Du Guanben, Zhang Lianpeng
Yunnan Provincial Key Laboratory of Wood Adhesives and Glued Products, Southwest Forestry University, Kunming 650224, Yunnan, China.
College of Biological, Chemical Sciences and Engineering, Jiaxing University, Jiaxing 314001, China.
Int J Biol Macromol. 2024 Oct;277(Pt 4):134498. doi: 10.1016/j.ijbiomac.2024.134498. Epub 2024 Aug 31.
In this study, a novel fluorescent probe, MAC-2, for the detection of Au was designed and synthesised using cellulose as a carrier combined with benzothiazole derivatives. The structure of the probe was confirmed by SEM, XRD, FTIR, and H NMR, also the optical properties of the product were investigated. MAC-2 showed bright green fluorescence under a 365 nm UV lamp and exhibited significant quenching behaviour toward Au. MAC-2 utilises more sustainable biomass resources, featuring green and biodegradable characteristics that meet environmental requirements. Compared with most reported probes, it exhibits notable fluorescence properties. The limit of detection (LOD) is as low as 0.057 μM, and the response time is 1 min. It also demonstrates good specific recognition and anti-interference abilities. In addition, a smartphone was used as a portable signal processing device to achieve rapid detection of Au concentration. Meanwhile, MAC-2 was successfully prepared as a fluorescent test strip, providing a potential application for the convenient detection of Au. The high sensitivity and selectivity exhibited by cellulose-based fluorescent probes in detecting Au offer valuable insights and new ideas for the detection of other metal ions and biomolecules. These inspirations will help promote the continuous development of research and applications in related fields.
在本研究中,设计并合成了一种用于检测金的新型荧光探针MAC-2,它以纤维素为载体并结合苯并噻唑衍生物。通过扫描电子显微镜(SEM)、X射线衍射(XRD)、傅里叶变换红外光谱(FTIR)和核磁共振氢谱(H NMR)对探针结构进行了确认,还研究了产物的光学性质。MAC-2在365 nm紫外灯下呈现亮绿色荧光,并对金表现出显著的猝灭行为。MAC-2利用了更可持续的生物质资源,具有绿色和可生物降解的特性,符合环境要求。与大多数已报道的探针相比,它具有显著的荧光性质。检测限(LOD)低至0.057 μM,响应时间为1分钟。它还表现出良好的特异性识别和抗干扰能力。此外,使用智能手机作为便携式信号处理设备实现了金浓度的快速检测。同时,成功制备了MAC-2荧光试纸条,为金的便捷检测提供了潜在应用。基于纤维素的荧光探针在检测金时表现出的高灵敏度和选择性,为其他金属离子和生物分子的检测提供了有价值的见解和新思路。这些启示将有助于推动相关领域研究和应用的持续发展。