3-T MR 引导聚焦超声丘脑切开术治疗心脏起搏器患者的震颤：病例系列及文献复习。

3-T MR-guided focused ultrasound thalamotomy for tremor in patients with a cardiac pacemaker: case series and review of the literature.

机构信息

1Department of Neurosurgery, Clinica Universidad de Navarra, Pamplona.

2Department of Neurosurgery, Hospital Universitario Germans Trias I Pujol, Badalona, Barcelona.

出版信息

Neurosurg Focus. 2024 Sep 1;57(3):E5. doi: 10.3171/2024.6.FOCUS24171.

DOI:10.3171/2024.6.FOCUS24171

PMID:39217637

Abstract

MR-guided focused ultrasound (MRgFUS) has proven its efficacy and safety for the treatment of essential tremor (ET) and/or Parkinson's disease (PD). However, having a cardiac pacemaker has been considered an exclusion criterion for the use of MRgFUS. Only 2 patients with a cardiac pacemaker treated with MRgFUS have been previously reported, both treated using 1.5-T MRI. In this paper, the authors present their experience performing 3-T MRgFUS thalamotomy in 4 patients with an implanted cardiac pacemaker. Treatments were uneventful regarding complications or severe side effects. MRgFUS using 3-T MRI was found to be an efficient and safe treatment for ET and/or PD in patients with an MRI-compatible pacemaker.

摘要

磁共振引导聚焦超声（MRgFUS）已被证明可有效且安全地治疗原发性震颤（ET）和/或帕金森病（PD）。然而，装有心脏起搏器一直被视为使用 MRgFUS 的排除标准。此前仅报道过 2 例装有心脏起搏器的患者接受 MRgFUS 治疗，均使用 1.5-T MRI 进行治疗。本文作者介绍了他们在 4 例装有心脏起搏器的患者中进行 3-T MRgFUS 丘脑切开术的经验。治疗过程中无并发症或严重副作用发生。对于装有 MRI 兼容起搏器的 ET 和/或 PD 患者，使用 3-T MRI 的 MRgFUS 被发现是一种有效且安全的治疗方法。