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产后出血时单纯结扎子宫动脉及单纯结扎髂内动脉后的妊娠结局与生育能力

Pregnancy outcomes and fertility after ligation of uterine artery only and hypogastric artery only in postpartum hemorrhage.

作者信息

Tokgöz Çakır Betül, Öztürk Çağatayhan, Aktemur Gizem, Karabay Gülşan, Şeyhanlı Zeynep, Sucu Sadun, Bucak Mevlüt, Bayraktar Burak, Ulusoy Can Ozan, Sağlam Erkan, Çakır Caner, İskender Can Tekin, Engin-Üstün Yaprak

机构信息

Department of Perinatology, Ankara Etlik City Hospital, Ankara, Turkey.

Department of Gynecologic Oncology, Ankara University Faculty of Medicine, Ankara, Turkey.

出版信息

J Turk Ger Gynecol Assoc. 2024 Aug 29;25(3):132-137. doi: 10.4274/jtgga.galenos.2024.2023-10-7.

Abstract

OBJECTIVE

To determine and compare pregnancy outcomes after bilateral uterine artery ligation (BUAL) or bilateral hypogastric artery ligation (BHAL) for postpartum hemorrhage (PPH).

MATERIAL AND METHODS

This retrospective cross-sectional study was conducted from January 2010 to June 2018 at a tertiary referral hospital. Patients who had undergone arterial ligation for PPH were included in the study. Patients who had undergone BUAL and BHAL were compared with a control group in terms of fertility and pregnancy outcomes.

RESULTS

A total of 156 patients were included, of whom 47 underwent BUAl, 59 underwent BHAL and 50 were in the control group. There was no significant difference between the groups in subsequent pregnancies in terms of the incidence of miscarriage, fetal growth restriction, preeclampsia, primary cesarean deliveries, and infertility (p>0.05). There was a significant difference between all groups in gestational age at birth and birthweight. Preterm birth was observed in 32.2% of patients in the BHAL group, and this rate was significantly higher than in the BUAL (12.8%) and control (6%) groups (p=0.001).

CONCLUSION

PPH is a life-threatening obstetric problem. The effects of interventions performed to reduce pelvic blood flow in patients may lead to persistent problems, such as preterm birth and low birth weight in the next pregnancy. However, these interventions do not appear to affect the risk of miscarriage. In subsequent pregnancies of patients who received BHAL, special attention should be paid to preterm birth.

摘要

目的

确定并比较双侧子宫动脉结扎术(BUAL)或双侧髂内动脉结扎术(BHAL)治疗产后出血(PPH)后的妊娠结局。

材料与方法

本回顾性横断面研究于2010年1月至2018年6月在一家三级转诊医院进行。纳入因PPH接受动脉结扎术的患者。将接受BUAL和BHAL的患者与对照组在生育能力和妊娠结局方面进行比较。

结果

共纳入156例患者,其中47例行BUAL,59例行BHAL,50例为对照组。各组后续妊娠在流产发生率、胎儿生长受限、子痫前期、首次剖宫产及不孕方面无显著差异(p>0.05)。各组在出生孕周和出生体重方面存在显著差异。BHAL组32.2%的患者出现早产,该比例显著高于BUAL组(12.8%)和对照组(6%)(p=0.001)。

结论

PPH是一种危及生命的产科问题。为减少患者盆腔血流而采取的干预措施的影响可能会导致持续性问题,如下次妊娠时早产和低出生体重。然而,这些干预措施似乎不影响流产风险。在接受BHAL的患者的后续妊娠中,应特别关注早产问题。

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本文引用的文献

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Int J Womens Health. 2020 Mar 6;12:151-158. doi: 10.2147/IJWH.S236443. eCollection 2020.
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Ligating Internal Iliac Artery: Success beyond Hesitation.结扎髂内动脉:犹豫之外的成功。
J Obstet Gynaecol India. 2016 Oct;66(Suppl 1):235-41. doi: 10.1007/s13224-016-0859-1. Epub 2016 Mar 14.
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Anatomical Study on the Variations in the Branching Pattern of Internal Iliac Artery.髂内动脉分支模式变异的解剖学研究
Indian J Surg. 2015 Dec;77(Suppl 2):248-52. doi: 10.1007/s12262-012-0785-0. Epub 2012 Dec 20.
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Consequences of hypogastric artery ligation, embolization, or coverage.腹下动脉结扎、栓塞或覆盖的后果。
J Vasc Surg. 2015 Nov;62(5):1340-7.e1. doi: 10.1016/j.jvs.2015.08.053. Epub 2015 Sep 19.

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