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生长激素分泌型垂体腺瘤与困难气道:清醒经口纤维光导喉镜插管法

Growth Hormone-Secreting Pituitary Adenoma and Difficult Airway: Awake Oral Fiberoptic Intubation Approach.

作者信息

Pathak Girish, Vijapurkar Swati, Kalbande Jitendra V, Chandana Daliboina T, Sandeep Gade

机构信息

Anesthesiology, All India Institute of Medical Sciences, Raipur, Raipur, IND.

Anesthesiology and Critical Care, All India Institute of Medical Sciences, Raipur, Raipur, IND.

出版信息

Cureus. 2024 Jul 31;16(7):e65889. doi: 10.7759/cureus.65889. eCollection 2024 Jul.

DOI:10.7759/cureus.65889
PMID:39219953
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11364523/
Abstract

Acromegaly is a rare endocrine disorder characterized by excessive growth hormone (GH) secretion, usually due to a pituitary adenoma. This condition leads to progressive somatic disfigurement, including enlarged hands, feet, and facial features, and is often associated with systemic complications such as cardiovascular disease, diabetes mellitus, and sleep apnea. Anesthesia for patients with acromegaly presents unique challenges due to the characteristic anatomical and physiological changes associated with the condition. Acromegaly, resulting from excessive GH secretion, often leads to difficult airway management, cardiovascular complications, and metabolic abnormalities. Transnasal transsphenoidal excision of pituitary adenoma is a minimally invasive surgical technique employed to remove pituitary tumors. This approach, which utilizes the nasal passages and sphenoid sinus to access the pituitary gland, offers several advantages, including reduced recovery time, minimal scarring, and lower risk of complications compared to traditional craniotomy. Awake fiberoptic intubation is one of the recommended strategies to secure an expected difficult airway such as in acromegaly. This case highlights the importance of preoperative planning and the role of an oral fiberoptic technique in managing the airway in surgeries like the transnasal approach.

摘要

肢端肥大症是一种罕见的内分泌疾病,其特征是生长激素(GH)分泌过多,通常由垂体腺瘤引起。这种情况会导致渐进性的身体畸形,包括手部、足部和面部特征增大,并且常与心血管疾病、糖尿病和睡眠呼吸暂停等全身并发症相关。由于与该疾病相关的特征性解剖和生理变化,肢端肥大症患者的麻醉面临独特的挑战。由生长激素分泌过多导致的肢端肥大症,常常会导致气道管理困难、心血管并发症和代谢异常。经鼻蝶窦垂体腺瘤切除术是一种用于切除垂体肿瘤的微创手术技术。这种方法利用鼻腔和蝶窦进入垂体,与传统开颅手术相比,具有恢复时间缩短、疤痕最小化和并发症风险较低等几个优点。清醒纤维光导喉镜插管是确保预期困难气道(如肢端肥大症患者)安全的推荐策略之一。本病例强调了术前规划的重要性以及口腔纤维光导技术在经鼻手术等气道管理中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/0d7d6fa8441d/cureus-0016-00000065889-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/9bd834b911ef/cureus-0016-00000065889-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/f4daf1cd2955/cureus-0016-00000065889-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/0d7d6fa8441d/cureus-0016-00000065889-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/9bd834b911ef/cureus-0016-00000065889-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/f4daf1cd2955/cureus-0016-00000065889-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d799/11364523/0d7d6fa8441d/cureus-0016-00000065889-i03.jpg

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本文引用的文献

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Awake tracheal intubation.清醒气管插管
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Pituitary Adenomas: From Diagnosis to Therapeutics.垂体腺瘤:从诊断到治疗
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Ultrasound guided lateral femoral cutaneous nerve (LFCN) block: safe and simple anesthesia for harvesting skin grafts.超声引导股外侧皮神经(LFCN)阻滞:安全简便的供皮区麻醉方法。
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