Wei Xue-Yan, Huo Hong-Chang, Li Xin, Sun Su-Li, Zhang Jun
Department of Outpatient, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050090, Hebei Province, China.
Department of Pediatric Surgery, Shijiazhuang Maternal and Child Health Hospital, Shijiazhuang 050090, Hebei Province, China.
World J Gastrointest Surg. 2024 Aug 27;16(8):2640-2648. doi: 10.4240/wjgs.v16.i8.2640.
Intussusception occurs in children and progresses rapidly. If not treated in time, it may lead to secondary complications such as intestinal perforation, which affect the quality of life and health of children. Surgery is the most common clinical treatment and has a good effect. However, the postoperative prognosis of children with intussusception has a correlation with the postoperative rehabilitation method. Therefore, in this study, we explored the relationship between postoperative rehabilitation, gastrointestinal function, and the expression of inflammatory factors in children with intussusception.
To explore the relationship between postoperative rehabilitation, gastrointestinal function, and inflammatory factor levels in children with intussusception.
The medical records of 18 children who were admitted to our hospital for intussusception surgery between October 2022 and May 2024 were retrospectively reviewed. The patients were divided into the routine nursing group ( = 6) and rehabilitation training group ( = 12) according to the postoperative rehabilitation method. The general data, gastrointestinal function, and inflammatory factor levels of the two groups were statistically analyzed. Pearson correlation analysis of gastrointestinal function, inflammatory factors, and postoperative rehabilitation was performed.
We found no significant intergroup differences in sex, age, or disease course ( > 0.05). The times to first defecation, bowel sound recovery, and anal exhaust were shorter and inflammatory factor levels were lower in the rehabilitation training group than in the routine nursing group ( < 0.05). Pearson correlation analysis showed that gastrin and motilin levels were positively correlated with postoperative rehabilitation ( < 0.05). Interleukin (IL)-2, IL-4, IL-6, IL-10, high-sensitivity C-reactive protein, and tumor necrosis factor-α levels were negatively correlated with postoperative rehabilitation ( < 0.05). Gastrointestinal function was positively correlated ( < 0.05), and levels of inflammatory factors were negatively correlated with postoperative recovery time ( < 0.05).
We found a positive correlation between gastrointestinal function and postoperative rehabilitation training, and a negative correlation between inflammatory factor levels and rehabilitation training in children with intussusception.
肠套叠多见于儿童，病情进展迅速。若不及时治疗，可能导致肠穿孔等继发性并发症，影响儿童的生活质量和健康。手术是最常见的临床治疗方法，效果良好。然而，肠套叠患儿术后的预后与术后康复方法有关。因此，在本研究中，我们探讨了肠套叠患儿术后康复、胃肠功能及炎症因子表达之间的关系。
探讨肠套叠患儿术后康复、胃肠功能及炎症因子水平之间的关系。
回顾性分析2022年10月至2024年5月在我院接受肠套叠手术的18例患儿的病历资料。根据术后康复方法将患者分为常规护理组（n = 6）和康复训练组（n = 12）。对两组的一般资料、胃肠功能及炎症因子水平进行统计学分析。对胃肠功能、炎症因子与术后康复进行Pearson相关性分析。
我们发现两组在性别、年龄或病程方面无显著组间差异（P > 0.05）。康复训练组首次排便时间、肠鸣音恢复时间和肛门排气时间均短于常规护理组，且炎症因子水平低于常规护理组（P < 0.05）。Pearson相关性分析显示，胃泌素和胃动素水平与术后康复呈正相关（P < 0.05）。白细胞介素（IL）-2、IL-4、IL-6、IL-10、高敏C反应蛋白和肿瘤坏死因子-α水平与术后康复呈负相关（P < 0.05）。胃肠功能呈正相关（P < 0.05），炎症因子水平与术后恢复时间呈负相关（P < 0.05）。
我们发现肠套叠患儿的胃肠功能与术后康复训练呈正相关，炎症因子水平与康复训练呈负相关。
