Chu Liangliang, Liu Xiaoyi, Xu Cuiping
School of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, China.
School of Nursing, Shandong Academy of Medical Sciences, Shandong First Medical University, Taian, Shandong, China.
Front Pediatr. 2024 Aug 16;12:1416383. doi: 10.3389/fped.2024.1416383. eCollection 2024.
The rising incidence of drug abuse among pregnant women has rendered neonatal opioid withdrawal syndrome a significant global health concern.
Databases including PubMed, Web of Science, the Cochrane Library, Embase, Elton B. Stephens. Company (EBSCO), China National Knowledge Infrastructure (CNKI), and Wanfang were searched for comparative studies of the Eat, Sleep, Console model vs. traditional assessment tools for neonatal opioid withdrawal syndrome. Two reviewers conducted literature searches, screened according to the inclusion criteria, extracted data, and independently verified accuracy. All meta-analyses were conducted using Review Manager Version 5.4.
In total, 18 studies involving 4,639 neonates were included in the meta-analysis. The Eat, Sleep, Console model demonstrated superior outcomes in assessing neonatal opioid withdrawal syndrome, significantly reducing the need for pharmacological treatment [risk ratio = 0.44, 95% confidence interval (CI) = 0.34-0.56, < 0.001], decreasing the length of hospital stay [standard mean difference (SMD) = -2.10, 95% CI = -3.43 to -0.78, 0.002], and shortening the duration of opioid treatment (SMD = -1.33, 95% CI = -2.22 to -0.45, 0.003) compared to the Finnegan Neonatal Abstinence Scoring System.
The Eat, Sleep, Console model is more effective than the Finnegan Neonatal Abstinence Scoring System in improving the assessment and management of neonatal opioid withdrawal syndrome.
孕妇药物滥用发生率的上升使新生儿阿片类药物戒断综合征成为一个重大的全球健康问题。
检索包括PubMed、科学网、考克兰图书馆、Embase、埃尔顿·B·斯蒂芬斯公司（EBSCO）、中国知网和万方在内的数据库，查找关于“进食、睡眠、安抚”模型与新生儿阿片类药物戒断综合征传统评估工具的比较研究。两名 reviewers 进行文献检索，根据纳入标准进行筛选，提取数据，并独立核实准确性。所有荟萃分析均使用Review Manager 5.4版进行。
荟萃分析共纳入18项研究，涉及4639名新生儿。与芬尼根新生儿戒断评分系统相比，“进食、睡眠、安抚”模型在评估新生儿阿片类药物戒断综合征方面显示出更好的结果，显著减少了药物治疗的需求[风险比=0.44，95%置信区间（CI）=0.34-0.56，<0.001]，缩短了住院时间[标准化均数差（SMD）=-2.10，95%CI=-3.43至-0.78，0.002]，并缩短了阿片类药物治疗的持续时间（SMD=-1.33，95%CI=-2.22至-0.45，0.003）。
在改善新生儿阿片类药物戒断综合征的评估和管理方面，“进食、睡眠、安抚”模型比芬尼根新生儿戒断评分系统更有效。
