Gherlan George S
Department of Infectious Diseases, "Carol Davila" University of Medicine and Pharmacy, Bucharest 050474, Romania.
World J Hepatol. 2024 Aug 27;16(8):1084-1090. doi: 10.4254/wjh.v16.i8.1084.
Zoonoses are responsible for many of all emerging infectious diseases as well as for those already established. is a rat-originated virus related to the hepatitis E virus but highly divergent genetically from this, with a high cross-species infection potential and zoonotic transmission. It can infect humans, leading to acute hepatitis, and is primarily transmitted through the consumption of contaminated water. was first discovered in Germany in 2010. The first human case was described in 2017 in Hong Kong in an immune-compromised patient. The first case of chronic infection with was described in 2023. A meta-analysis based on 38 studies published between 2000 and 2023 identified 21 cases in humans described up to this date and 489 infections in different animals. Raising awareness regarding this virus is essential, as there are probably many cases that remain undiagnosed, and the virus even has the ability to produce chronic infections in selected patients.
人畜共患病是许多新出现的传染病以及那些已存在的传染病的病因。[病毒名称]是一种源自大鼠的病毒，与戊型肝炎病毒有关，但在基因上与后者高度不同，具有很高的跨物种感染潜力和人畜共患传播能力。它可感染人类，导致急性肝炎，主要通过饮用受污染的水传播。[病毒名称]于2010年在德国首次被发现。2017年在香港一名免疫功能低下的患者中描述了首例人类病例。2023年描述了首例[病毒名称]慢性感染病例。一项基于2000年至2023年发表的38项研究的荟萃分析确定，截至目前已描述了21例人类病例以及不同动物中的489例感染病例。提高对这种病毒的认识至关重要，因为可能有许多病例仍未被诊断出来，而且该病毒甚至有能力在特定患者中引发慢性感染。
