Adachi Mio, Oda Goshi, Hara Masatake, Kumaki Yuichi, Fujioka Tomoyuki, Ishiba Toshiyuki, Tateishi Ukihide
Department of Breast Surgery Tokyo Medical and Dental University Hospital, Yushima 1-5-45 Bunkyo-ku, Tokyo 113-8519, Japan.
Department of Radiology Tokyo Medical and Dental University Hospital, Yushima 1-5-45 Bunkyo-ku, Tokyo 113-8519, Japan.
Case Rep Surg. 2024 Aug 24;2024:5354241. doi: 10.1155/2024/5354241. eCollection 2024.
Autoimmune neutropenia (AIN) is an extremely rare condition, and there is no effective treatment option for this disorder. AIN can cause major complications in patients with perioperative infection. Herein, we present a 56-year-old female patient who was scheduled for breast cancer surgery. However, she was unexpectedly diagnosed with AIN. Thus, the surgery was postponed, and endocrine therapy was started. After 7 months of treatment, the surgery was performed. Granulocyte colony-stimulating factor was administered before the surgery, but the patient's neutrophil count did not increase. Thus, levofloxacin was administered during the surgery. The patient had fever (38.6°C) 1 day after the surgery. Her surgical wound did not present with redness, and there were no other signs of infection. The fever subsided on the second day after the surgery. Nevertheless, antibiotics were administered for 5 days. The patient was discharged on the sixth day after the surgery.
自身免疫性中性粒细胞减少症（AIN）是一种极其罕见的病症，目前尚无针对该疾病的有效治疗方案。AIN可导致围手术期感染患者出现严重并发症。在此，我们报告一名56岁的女性患者，她原计划接受乳腺癌手术。然而，她意外被诊断出患有AIN。因此，手术被推迟，并开始了内分泌治疗。经过7个月的治疗后，进行了手术。术前给予了粒细胞集落刺激因子，但患者的中性粒细胞计数并未增加。因此，术中给予了左氧氟沙星。患者术后第1天出现发热（38.6°C）。她的手术伤口没有发红，也没有其他感染迹象。术后第二天发热消退。尽管如此，抗生素仍使用了5天。患者术后第六天出院。
